In this paper, the use of silica gel column chromatography to chloroform - methanol as the mobile phase gradient elution of the product of two reactions to separation and purification, the two kinds of compounds, by means of the application of nuclear magnetic resonance identification of the two kinds of compounds, are XX and yy. In this paper, the structural modification ligustrazine, isolated two kinds of compounds, for the subsequent modification of the structure of this compound to provide a certain amount of experience