刘培论文发表

发表代表性论文目录[1] 段金廒*,吴启南,宿树兰,周荣汉.中药资源化学学科的建立与发展[J].中草药, 2012, 43: 1665-1671.[2] 段金廒*.中药资源化学研究技术体系的建立及其应用[J].中国药科大学学报,2012,4:289-292.[3] 段金廒*, 严辉, 宿树兰, 钱大玮, 吴启南, 周荣汉. 药材适宜采收期综合评价模式的建立与实践. 中草药, 2010, 41 (11): 1755-1760.[4] 段金廒*, 宿树兰, 吕洁丽, 严辉, 丁安伟. 药材产地加工传统经验与现代科学认识. 中国中药杂志, 2009, 34（24）: 3151-3157.[5] 段金廒*, 宿树兰, 钱大玮, 唐于平, 周荣汉. 中药资源化学研究思路方法与进展. 中国天然药物, 2009, 7 (5): 333-340.[6] 段金廒*, 肖小河, 宿树兰, 赵润怀, 严辉. 中药材商品规格形成模式的探讨——以当归为例. 中国现代中药, 2009, 11 (6): 14-17.[7] 段金廒*, 周荣汉, 宿树兰, 丁安伟, 吴启南. 我国中药资源科学发展现状及展望. 自然资源学报, 2009, 24 (3): 378-386.[8] 段金廒*, 宿树兰, 严辉, 钱大玮. 药材初加工“杀青”环节与药材品质形成的探讨. 中药材, 2011, 24(1): 1-6.[9] 宿树兰, 段金廒*, 欧阳臻, 郭盛, 刘利. 我国桑属(Morus L.)药用植物资源化学研究进展. 中国现代中药, 2012, 14(7): 1-6.[10] 严辉,段金廒*,王瑞琪,郭增祥,钱大玮,宋秉生,何子清,高鸿英.岷县当归产量预报模型研究[J].中药材,2012,4:511-514.[11] 段金廒*,张伯礼,范欣生,张艳军,高月,林娜,钟赣生.中药配伍禁忌研究思路与技术体系框架[J].世界科学技术(中医药现代化),2012,3:1537-1546.[12] 段金廒*,宿树兰,范欣生,钱大玮,唐于平,尚尔鑫,郭建明,刘培.基于药物相互作用探讨中药七情合和相反/相恶/相畏配伍禁忌作用模式与机制[J].世界科学技术(中医药现代化),2012,3:1547-1552.[13] 陈艳琰,钱大玮,尚尔鑫,钱叶飞,刘培,宿树兰,郭建明,唐于平,段金廒*.基于化学成分相互作用探讨芫花与甘草配伍禁忌的机制[J].药学学报,2012,8:1043-1048.[14] 华永庆,段金廒,钱大玮,江曙,丁爱华,宿树兰,郭建明. 胃肠道系统功能评价技术体系的建立及其在中药配伍禁忌研究中的应用. 世界科学技术—中医药现代化, 2012, 14 (3): 17-25.[15] 钱叶飞,尚尔鑫,段金廒*,钱大玮,唐于平. 基于液质联用数据库技术的中药及天然药物化学成分快速鉴定方法的建立. 中国中药杂志, 2012, 37 (21): 3256-3263.[16] 段金廒*, 吴勉华, 范欣生, 张艳军, 刘成海, 唐于平, 尚尔鑫, 王中越. 中医方药量-效关系科学问题的探讨. 南京中医药大学学报, 2010, 26 (1): 1-6.[17] 宿树兰, 段金廒*, 李文林, 唐于平, 范欣生. 基于物质基础探讨中药“十八反”配伍致毒/增毒机制. 中国实验方剂学杂志, 2010, 16 (1): 123-129.[18] 段金廒*, 宿树兰, 唐于平, 范欣生. 中药药对配伍组合的现代认识. 南京中医药大学学报, 2009, 25 (5): 330-333.[19] 段金廒*, 范欣生, 宿树兰, 唐于平, 尚尔鑫, 李文林, 郭建明, 华永庆. 中药及方剂量效关系的研究进展与思考. 南京中医药大学学报, 2009, 25 (4): 241-245.[20] 段金廒*, 陆茵,陈建伟, 丁安伟, 孙世发, 朱荃, 范欣生. 方剂现代研究的思路与方法. 南京中医药大学学报(自然科学版), 2006, 22 (1): 1-3.[21]Shulan Su, Jin-Ao Duan*, Peijuan Wang, Pei Liu, Jianming Guo, Erxin Shang, DaweiQian, Yuping Tang, Zongxiang Tang. A metabolomic study of biochemical changes in the plasma and urine of primary dysmenorrhea patients using UPLC-MS coupled with pattern recognition approach [J]. Journal of Proteome Research, 2013, 12 (2): 852–865. (IF=5.113) [22]Hongyue Ma, Min Hong, Jinao Duan*, Pei Liu, Xinsheng Fan, Erxin Shang, Shulan Su, Jianming Guo, DaweiQian, Yuping Tang. Altered cytokine gene expression in peripheral blood monocytes across the menstrual cycle in primary dysmenorrhea: a case-control study [J]. PLos One, 2013, 8(2): e55200. (IF=4.092) [23]Pei Liu, Jinao Duan*, Peijuan Wang, DaweiQian, JianmingGuo, Erxin Shang, Shulan Su, Yuping Tang, Zongxiang Tang. Biomarkers of primary dysmenorrhea and herbal formula intervention: an exploratory metabonomics study of blood plasma and urine [J]. Molecular BioSystems, 2013, 9 (1): 77–87. (IF=3.534)[24] Shulan Su, YongqingHua, Yanyan Wang, Wei Gu, Wei Zhou,Jin-ao Duan*, Haifeng Jiang, Ting Chen, Yuping Tang. Evaluation of the anti-inflammatory and analgesic properties of individual andcombined extracts from Commiphoramyrrha, and Boswelliacarterii.Journal of Ethnopharmacology, 2012, 139: 649-656.25] L. Yu, B.P. Jiang,D. Luo, X.C. Shen, S. Guo, J.A. Duan*, Y.P. Tang. Bioactive components in the fruits of Ziziphusjujuba Mill. against theinflammatory irritant action of Euphorbia plants. Phytomedicine,2012, 19 (3-4): 239-244.[26] Li Liu, Jin-aoDuan*, Yuping Tang, JianmingGuo, Nianyun Yang, Hongyue Ma, Xuqin Shi. Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation. Journal of Ethnopharmacology, 2012, 139 (1): 381-387.[27] Hanqing Wang, Sheng Guo, DaweiQian, YefeiQian, Jin-aoDuan. Comparative analysis of quinolizidine alkaloids from different parts of Sophoraalopecuroides seeds by UPLC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 2012, 67-68: 16-21.[28] Wei-Wei Tao, Jin-Ao Duan,* Nian-Yun Yang, Sheng Guo, Zhen-Hua Zhu,Yu-Ping Tang and Da-Wei Qian. Determination of Nucleosides andNucleobases in the Pollen of TyphaAngustifolia by UPLC-PDA-MS. Phytochemical Analysis, 2012, 23 (4): 373-378.[29] Rui Liu, Jin-ao Duan*, Sheng Guo, Jian-mingGuo, Da-wei Qian, Yu-ping Tang. Development of a fingerprint method for animal horn classification by liquid chromatography coupled with hierarchical clustering analysis. Journal of Liquid Chromatography & Related Technologies, 2012, 35 (2):205-214.[30] Li Liu, Hongyue Ma, Yuping Tang, Wenxing Chen, Yin Lu, JianmingGuo,Jin-ao Duan*. Discovery of estrogen receptor a modulators from natural compounds in Si-Wu-Tang series decoctions using estrogen-responsive MCF-7 breast cancer cells. Bioorganic & Medicinal Chemistry Letters, 2012, 22 (1): 154-163[31] Pei Liu, Jin-ao Duan*, Jian-mingGuo, Er-Xin Shang, Da-weiQian,Shu-lan Su and Yu-ping Tang. Identification of major chemical constituents and their metabolites in rat plasma and various organs after oral administration of effective Xiang-Fu-Si-Wu Decoction fraction by UPLC-Q-TOF-MS and Metabolynx. Journal of Liquid Chromatography & Related Technologies, 2012, DOI:10.1080/10826076.2012.698676.[32] Wei-Wei Tao, Jin-AoDuan*, Nian-Yun Yang, Yu-Ping Tang, Meng-Zhu Liu, Ye-FeiQian. Antithrombotic phenolic compounds from Glycyrrhiza uralensis.Fitoterapia,2012, 83(2):422-425.[33] G. Yu, Y.X. Ma, J.-A. Duan*, B.S. Song, Z.Q. He. Identification of differentially expressed genes involved in early bolting of Angelica sinensis (Apiaceae). Genetics and Molecular Research, 2012, 11 (1): 494-502.[34] Sheng Guo,Jin-ao Duan*, Yuping Tang, DaweiQian, Zhenhua Zhu, YefeiQian, ErxinShang, Shulan Su. UHPLC-TOFMS coupled with chemometric method as a powerful technique for rapid exploring of differentiating components between two Ziziphus species Journal of Separation Science,2011, 34(6): 659-666.[35] Shulan Su, Tuanjie Wang,Jin-Ao Duan*, Wei Zhou, Yong-Qing Hua, Yu-Ping Tang, Li Yu, Da-Wei Qian. Anti-inflammatory and analgesic activity of different extracts of Commiphoramyrrha. Journal of Ethnopharmacology, 2011, 134 (2): 251-258.[36] Sheng Guo, Jin-ao Duan*, Yu Ping Tang, ShuLan Su, Da Wei Qian. Triterpenoid acids from Ziziphus jujube. Chemistry of Natural Compounds, 2011, 47 (1): 138-139.[37] Rui Liu, Jin-ao Duan*, Min Wang, Erxin Shang, JianmingGuo, Yuping Tang. Analysis of active components of rhinoceros, water buffalo and yak horns using two-dimensional electrophoresis and ethnopharmacological evaluation. Journal of Separation Science,2011, 34 (3): 354-362.[38] Pei Liu, Jin-ao Duan*, Yong qingHua, Yu ping Tang, Xin Yao, Shulan Su. Effects of Xiang-Fu-Si-Wu Decoction and its main components for dysmenorrhea on uterus contraction. Journal of Ethnopharmacology, 2011, 133 (2): 591-597.[39] JianmingGuo, Erxin Shang, Jin-ao Duan*, Yuping Tang, DaweiQian. Determination of ligustilide in the brains of freely moving rats using microdialysis coupled with ultra performance liquid chromatography/mass spectrometry. Fitoterapia, 2011, 82 (3): 441-445.[40] JianmingGuo, CaifuXue, Jin-ao Duan,Er-xin Shang, DaweiQian, Yuping Tang, QiangOuyang, Mei Sha. Fast characterization of constituents in HuangKui capsules using UPLC-QTOF-MS with collision energy and MassFragment software. Chromatographia, 2011, 73 (5-6): 447-456.[41] CaifuXue, JianmingGuo, DaweiQian*, Jin-ao Duan*, Erxin Shang, Yan Shu, Yuwei Lu. Identification of the potential active components of Abelmoschusmanihot in rat blood and kidney tissue by microdialysis combined with ultra-performance liquid chromatography/ quadrupole time-of-flight mass spectrometry. Journal of Chromatography B, 2011, 879 (5-6): 317-325.[42] Shulan Su, JianmingGuo, Jin-ao Duan*, Tuanjie Wang, Erxin Shang, DaweiQian, Yuping Tang, Anwei Ding. Ultra-performance liquid chromatography-tandem mass spectrometry analysis of the bioactive components and their metabolites of ShaofuZhuyu decoction active extract in rat plasma. Journal of Chromatography B, 2010, 878 (3-4): 355–362.[43] Min Zhu, Yuping Tang,Jin-ao Duan*, JianmingGuo, ShengGuo, Shulan Su, Erxin Shang, Dawei Qian, Anwei Ding. Roles of paeoniflorin and senkyunolide I in SiWu decoction on antiplatelet and anticoagulation activitiesJournal of Separation Science,2010, 33 (21), 3335–3340.[44] Li Liu, Hongyue Ma, Nianyun Yang, Yuping Tang, JianmingGuo, Weiwei Tao, Jin-ao Duan*. A series of natural flavonoids as thrombin inhibitors: structure-activity relationships Thrombosis Research, 2010, 126 (5): 365–378.[45] Li Liu, Jin Ao Duan*, Yu Ping Tang, Hong Yue Ma, ShuLan Su, Jian Ming Guo, Yong Qing Hua. The protective effects of the active fraction of ShaofuZhuyu decoction on hydrogen peroxide-induced oxidative injury in vascular smooth muscle cells. Molecules, 2010, 15 (8), 5066–5078.[46] Yuping Tang, Min Zhu, Sheng Yu, YongqingHua, Jin-Ao Duan*, Shulan Su, Xu Zhang, Yin Lu, Anwei Ding. Identification and comparative quantification of bio-active phthalides in essential oils from Si-Wu-Tang, Fo-Shou-San, Radix Angelica and RhizomaChuanxiong. Molecules, 2010, 15(1), 341–351.[47] ShulanSu, YongqingHua, Jin-Ao Duan*, WeiZhou, ErxinShang, YupingTang. Inhibitory Effects of Active Fraction and Its Main Components of ShaofuZhuyu Decoction on Uterus Contraction. American Journal of Chinese Medicine, 2010, 38 (4): 777–787.[48] Wei Zhou, ShuLan Su*, Jin-Ao Duan*, Jian Ming Guo, Da Wei Qian, ErXin Shang, Jin Zhang. Characterization of the active constituents in Shixiao San using bioactivity evaluation followed by UPLC-QTOF and Markerlynx analysis. Molecules, 2010, 15 (9): 6217–6230.[49] Jin-ao Duan*, PengfeiHou, Yuping Tang, Pei Liu, Shulan Su, Hanqing Liu. A new sesquiterpene and other constituents fromSaussurealappa root,Natural Product Communications, 2010, 5 (10): 1531-1534.[50] Sheng Guo, Jin-Ao Duan*, Yu-Ping Tang, Zhen-Hua Zhu, Ye-FeiQian, Nian-Yun Yang, Er-Xin Shang, Da-Wei Qian. Characterization of nucleosides and nucleobases in fruits of Ziziphusjujuba by UPLC-DAD-MS. Journal of Agricultural and Food Chemistry, 2010, 58 (19), 10774–10780.[51] Sheng Guo,Jin-Ao Duan*, Yu-Ping Tang, Nian-Yun Yang, Da-Wei Qian, Shu-Lan Su, Er-Xin Shang. Characterization of triterpenic acids in fruits of Ziziphus species by HPLC-ELSD-MS. Journal of Agricultural and Food Chemistry,2010, 58 (10), 6285–6289.[52] Pei Liu, Li Liu, Yu Ping Tang,Jin Ao Duan*, Nian Yun Yang. A new cerebroside and its anti-proliferation effect on VSMCs from the radix of Cyperusrotundus L. Chinese Chemical Letters, 2010, 21 (5): 606–609.[53] Wei Wei Tao, Nian Yun Yang, Li Liu, Jin-Ao Duan*, De Kang Wu, Da Wei Qian, Yu Ping Tang. Two new cerebrosides from the pollen of Typhaangustifolia. Fitoterapia. 2010, 81 (3): 196–199.[54] Wei Wei Tao, NianYun Yang,Jin-Ao Duan*, De Kang Wu, ErXin Shang, Da Wei Qian, Yu Ping Tang. Two new nonacosanetriols from the pollen of Typhaangustifolia. Chinese Chemical Letters, 2010, 21 (2): 209–212.[55] Ying Chen, Jin-ao Duan*, DaweiQian, JianmingGuo, Bingsheng Song, Ming Yang. Assessment and comparison of immunoregulatory activity of four hydrosoluble fractions of Angelica sinensis in vitro on the peritoneal macrophages in ICR mice. International Immunopharmacology, 2010, 10 (4): 422–430.[56] Rui Liu, Min Wang,Jin-ao Duan*, Jian-mingGuo, Yu-ping Tang. Purification and identification of three novel antioxidant peptides from Cornububali (water buffalo horn). Peptides, 2010, 31 (5): 786–793.[57] Nian-Yun Yang, Wei-Wei Tao, Min Zhu, Jin-Ao Duan*, Jian-Guo Jiang. Two new isopimaranediterpenes from the feces of Trogopterusxanthipes. Fitoterapia, 2010, 81 (5): 381-384.[58] Nian Yun Yang, Jin-Ao Duan*, ErXin Shang, Li Juan Tian. Analysis of Sesquiterpene Lactones in Eupatorium lindleyanum by HPLC-PDA-ESI-MS/MS. Phytochemical Analysis, 2010, 21 (2): 144–149.[59] Nian-Yun Yang, Li Liu, Wei-Wei Tao, Jin-Ao Duan*, Li-Juan Tian. Diterpenoids from Pinusmassoniana resin and their cytotoxicity against A431 and A549 cells. Phytochemistry, 2010, 71 (13): 1528–1533.[60] Nian Yun Yang, Wei Wei Tao, Jin-Ao Duan, Antithrombotic flavonoids from the faeces of Trogopterusxanthipes.Natural Product Research, 2010, 24 (19): 1843–1849.[61] JianmingGuo, Jin-ao Duan*, Yuping Tang, NingJia, Xinghu Li, Ji Zhang. Fast onset of action and the analgesic and sedative efficacy of essential oil from RhizomaChuanxiong after nasal administration. Pharmazie, 2010, 65 (4): 296–299.[62] JianmingGuo, Erxin Shang,Jin-ao Duan*, Yuping Tang, DaweiQian, Shulan Su. Fast and automated characterization of major constituents in rat biofluid after oral administration of Abelmoschusmanihot extract using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry and MetaboLynx. Rapid Communications in Mass Spectrometry, 2010, 24 (4): 443–453.[63] YueGu, DaweiQian*, Jin-ao Duan*, Zhenzhong Wang, JianmingGuo, Yuping Tang, Sheng Guo. Simultaneous determination of seven main alkaloids of Chelidoniummajus L. by ultraperformance LC with photodiode-array detection. Journal of Separation Science, 2010, 33 (8), 1004–1009.[64] Rui Liu, Min Wang, Jin-Ao Duan*. Antipyretic and antioxidant activities of the aqueous extract of Cornububali (Water Buffalo Horn). The American Journal of Chinese Medicine, 2010, 38 (2): 293–306.[65] 朱振华, 尚尔鑫, 段金廒*, 钱大玮, 唐于平. 中药方剂化学成分液质联用分析中标准质谱库的建立和应用. 分析化学, 2010, 38 (11): 1588-1592.[66] Jie Li Lü, Jing Zhao, Jin-Ao Duan*, Hui Yan, Yu Ping Tang, Lai Bin Zhang. Quality evaluation of Angelica sinensisby simultaneous determination of ten compounds usingLC-PDA. Chromatographia, 2009, 70 (3-4): 455-465.[67] Jie Li Lü,Jin Ao Duan*, Yu Ping Tang, Nian Yun Yang, Lai Bin Zhang. Phthalide mono- and dimers from the radix of Angelica sinensis. Biochemical Systematics and Ecology, 2009, 37 (4): 405-411.[68] XiangchunShen, Yuping Tang, Ruihui Yang, Li Yu, Taihui Fang,Jin-ao Duan*. The protective effect of Zizyphus jujube fruit on carbon tetrachloride-induced hepatic injury in mice by anti-oxidative activities. Journal of Ethnopharmacology, 2009, 122 (3): 555–560.[69] Sheng Guo, Jin-ao Duan*, Yuping Tang, Shulan Su, Erxin Shang, Shumao Ni, DaweiQian. High-performance liquid chromatography—two wavelength detection of triterpenoid acids from the fruits of Ziziphusjujuba containing various cultivars in different regions and classification using chemometric analysis. Journal of Pharmaceutical and Biomedical Analysis, 2009, 49 (5): 1296–1302[70] Sheng Guo, Yu Ping Tang, Jin-Ao Duan*, ShuLan Su, An Wei Ding. Two new terpenoids from fruits ofZiziphus jujube. Chinese Chemical Letters, 2009, 20 (2): 197–200.[71] ShuLan Su, Jin-Ao Duan*, Yu Ping Tang, Xu Zhang, Li Yu, FengRong Jiang, Wei Zhou, Dan Luo, An Wei Ding. Isolation and biological activities of neomyrrhaol and other terpenes from the resin of Commiphoramyrrha. Planta Medica, 2009, 75 (4): 351–355.[72] Nian Yun Yang, Wei Wei Tao, Jin-AoDuan*, Jian Ming Guo, Ling Ling Cao. Four new fatty acid esters from the feces of Trogopterusxanthipes. Lipids, 2009, 44 (9): 849–853.[73] Nian Yun Yang, Jin-Ao Duan*, Da Wei Qian. Simultaneous quantification of four sesquiterpene lactones inEupatorium lindleyanum DC. by RP-LC.Chromatographia,2009, 70 (1): 205–209.[74] Nian Yun Yang, Wei Wei Tao, Jin-Ao Duan* Three new lipids from the seeds of Trogopterusxanthipes. Journal of Chemical Research, 2009, (7): 423-426.[75] Nianyun Yang, Weiwei Tao,Jin-ao Duan*. Determination of Biflavones from Trogopterus Feces by HPLC.Journal of Food and Drug Analysis, 2009, 17 (5): 376–379.[76] Nianyun Yang, Weiwei Tao, Jin-ao Duan*. Four new long-chain aliphatics from the feces of Trogopterusxanthipes. Journal of Asian Natural Products Research, 2009, 11 (12): 1302– 1309.[77] JianmingGuo, Jin-ao Duan*, Erxin Shang, Yuping Tang, DaweiQian. Determination of ligustilide in rat brain after nasal administration of essential oil from RhizomaChuanxiong. Fitoterapia,2009, 80 (3): 168–172.[78] Jin-ao Duan*, Liuying Wang, ShihuiQian, ShulanSu, Yuping Tang. A New Cytotoxic PrenylatedDihydrobenzofuran Derivative and Other Chemical Constituents from the Rhizomes of Atractylodeslancea DC. Archieves of Pharmacal Research,2008, 31 (8): 965-969.[79] Shulan Su, YongqingHua, Jin-ao Duan*, Erxin Shang, Yuping Tang, XingjieBao, Yin Lu, Anwei Ding. Hypothesis of active components in volatile oil from a Chinese herbs formulation, ‘Shao-Fu-Zhu-Yu Decoction’, using GC-MS and Chemometrics. Journal of Separation Science,2008, 31 (6): 1085-1091.[80] Shulan Su, Li Yu, YongqingHua,Jin-ao Duan*, Haishan Deng, Yuping Tang, Yin Lu, Anwei Ding. Screening and analysis of potential bioactive components from ShaofuZhuyu decoction, using human umbilical vein endothelial cell extract and high performance liquid chromatography coupled with Q-TOF/MS spectrometry, Biomedical Chromatography,2008, 22 (12): 1385-1392.[81] Jie Li Lü, Jin-Ao Duan*, Yu Ping Tang, Two new ceramides from the radix of Angelica sinensis, Journal of Chemical Research, 2008, (11), 658-661.[82] YongqingHua, Shulan Su, Jin-ao Duan*, Qiujuan Wang, Yin Lu, Long Chen. Danggui–Shaoyao–San, a traditional Chinese prescription, suppresses PGF2a production in endometrial epithelial cells by inhibiting COX-2 expression and activity,Phytomedicine, 2008, 15 (12): 1046-1052.

随着医药事业的迅猛发展,社会对药学人才要求越来越高。下文是我为大家蒐集整理的关于的内容，欢迎大家阅读参考!

谈临床中药学实践与思考

【摘要】目的：分析临床中药学的实践和思考。方法：结合本院临床中医学的具体情况，对临床中医学的内容、模式、问题进行探讨。结果：加强临床中医学的实践，能让中药效用得以充分发挥，在对临床疗效进行提升的同时，还能让治疗安全性得以有效提高。结论：在医疗机构中开展临床中医学实践，能让临床疗效显著提高，同时不断提升临床药师的综合素质。

【关键词】临床中药学;实践;思考

临床中药学作为最近几年形成的新型学科，是一种临床药学[1]。临床中药学的目标是在实用和科学的基础上，让药物效用得以充分发挥，让患者安全性得以有效提升，全部临床中药的研究都存在可行性，能对患者病痛进行有效治疗[2]。本研究主要分析了临床中药学的内容、模式、问题，同时进行了认真思考，现做如下总结。

一、临床中药学的实践分析

1.1临床中药学的内容分析

临床中药学的研究内容主要为在对疾病进行预防和治疗时，中药起到的作用，并对中药的安全性、合理性和有效性进行分析探讨[3]。临床中药学的内容主要为药动学，临床治疗期间的中药疗效、临床用药合理性、有无副作用，对疾病治疗中的中药相互配合进行研究，同时开展临床试验，并评价药效的各个方面等。临床中药学的意义是在临床治疗中让中药的药效得以充分发挥，同时在中医理论指导下，对于临床治疗和患者康复具有非常重要的意义[4]。

1.2让中药师的综合素质全面提高

我国的教育明确规定，在中医药的高等教育中，应让学生分两阶段来对药学和医学知识进行学习，在对相关医学知识进行学习时，只能对中药学的表层知识进行粗略了解，要想让中药师综合素质快速提升，医疗机构常常邀请中医药学的专家来培训中药师，让中药师学习和掌握更多的中药学知识，在中药师了解和掌握相关的理论知识后，则会组织开展临床中药学实践。

1.3实施个性化用药

对于临床中药师来讲，在对普通患者进行用药合理性的指导时，还应保证特殊患者的用药合理性，如妇女、儿童以及老年人群等，除此之外还应对患者进行合理指导，让患者用药安全性得以有效保证。不仅需要对一般患者的合理用药进行指导，同时还需要对特殊患者的合理用药进行指导。

1.4对临床常见病和多发病进行了解

对于临床中药师来讲，在对培训的中医药学理论内容进行熟练掌握的基础上，还应对日常生活中患者常见的部分疾病，或者在某个季节部分疾病的发生率较高等，中药师应熟练掌握这些疾病的临床特征、疾病控制情况以及治疗方法等，为结合患者的具体病情提出科学和合理的治疗措施，同时还应制定治疗的紧急方案。

1.5对教学能力进行掌握

对于临床中药师来讲，向临床药师定期解释和讲解有关临床中药学的特点、基本内容、使用方法、使用剂量以及副作用等情况也是其基本任务之一[5];除此之外还应讲解部分药物联合西药应用对疾病的治疗效果，药物在使用过程中的相关注意事项等，避免临床药师因为不了解中药药性等情况而导致医疗事故，让临床药师的中药应用能力有效提高。

二、临床中药学的思考

2.1坚持以病人为中心的观念

分析现阶段的实际情况可以发现，医疗机构的大部分临床药师对自己药物使用情况方面的工作都比较重视，然而去并没有重视开展这些工作的最终目标是让患者的疾病得以有效治愈，在医疗活动中患者才是核心，所有工作的开展都应为患者提供服务。因此对于临床药师来讲，不但需要自己了解和掌握中药的药理、药性，同时还应对患者进行指导，让其用药合理性提高，防止部分因为部分临床医护人员粗心大意而发生药物用错的情况。让患者来监督医疗工作，能让医护人员的工作质量得以有效提高。

2.2创新临床中药的模式

要想让中药的药效能得以充分发挥，就需要对临床中药模式进行不断探索，通过科学和合理的临床中药学指导，中医药人员应加强和西药学工作人员的交流沟通，积极探寻相关药性是否能联合应用来对某种疾病进行治疗，怎样有效控制治疗期间的不良反应，在保证治疗安全的基础上，让药物的临床治疗效果得以充分发挥。

2.3对中药学知识进行广泛宣传

医院应定期进行中药学知识宣传手册的发放，积极组织开展科普知识讲座，对中药学的使用方法、使用剂量、配伍禁忌、不良反应和相关注意事项等进行积极宣传，患者也可以学习宣传手册，并参加知识讲座，医院专家可以深入社群进行宣讲，向普通老百姓普及中药学知识。

2.4树立良好的养生理念

人们应在日常生活中加强疾病的预防，对养生加以关注和重视。中医学研究结果显示，通过合理饮食和日常锻炼能对疾病进行有效预防，通过日常锻炼能让机体免疫力显著提高，人们日常生活中所食用的食物也可以作为中药来对疾病进行治疗。日常饮食中如果人们能合理食用，则能让身体素质有效增强。

2.5服务多样化

安排专业人员定期评价处方的价值和合理性，防止出现药物滥用的现象。医疗机构内部应设定专门的药物咨询平台，为不清楚药物的患者或者医生提供药物咨询服务，对于临床药师来讲，在日常工作中应提高工作积极性和主动，对患者服药后的不良反应发生情况进行了解和询问，同时结合患者的实际情况提出意见。

三、讨论

本研究主要对我院的临床中药学的实践情况进行了分析和探讨，同时经过分析发现，临床药师在日常工作中，应通过提高素质、掌握教学能力、合理用药、创新模式、多样化服务和加强宣传，让临床中药学的效用得以充分发挥，为中药的临床应用提供科学依据。

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