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Objective: Through the study of animal experiments to observe the United Yishen soup benazepril 5 / 6 nephrectomized rats renal function improved efficacy and reduced TGF-β1 expression in renal tissue and other advantages, and to explore the soup Yishen possible to improve the renal function of mechanism of action. Methods: 1. Select SPF class healthy adult male SD rats with 50 only as the research object, adaptive feeding one weeks later, 10 randomly selected as the sham-operated group (A group), and the remaining 40 with 5 / 6 nephrectomy CRF-made law model. 2. After the success of model selection criteria in line with the study group 32 rats were divided into B: model group, 8; C groups: benazepril group 8; D group: the Chinese Medicines Board 8; E Group : Yishen Decoction United benazepril group referred to as traditional Chinese and western medicine group of eight, together with the A Group of 5 Group. 3. Successful modeling start after delivery, the groups were given corresponding drugs decoction. 4. The end of the experiment 24 hours after the detection of urinary protein and blood BUN, Scr, RBC, Hb, and renal histology observation and renal tissue TGF-β1 expression assay. Results: 1. The general situation: during the experiment, sham-operated rats demonstrated alertness, quick reaction, dense fur, clean and shiny, growth, consumption and the activities had no significant abnormalities, weight gain; model group was significant malnutrition, make them apathetic, slow activity, loss of appetite, fluffy fur, haggard Matte, died in the course of treatment at 2, probably because of renal failure due consideration; benazepril rats than sham-operated group spirit apathetic, slow activity, fur, fluffy; medicine the performance of rats with similar benazepril group; WM rats with sham-operated rats without much difference in general performance, but dry dark fur. 2. Of blood BUN, Scr impact: benazepril group, traditional Chinese medicine group, in the WM group significantly decreased BUN, Scr level, compared with the model group has significant difference (P <), but still high in sham-operated group; traditional Chinese and western medicine group and the Chinese medicine group, benazepril group has significant difference (P <); Chinese medicine group and the benazepril group was no significant difference (P> ). 3. Hematology impact: Chinese medicine group and the TCM-WM group was significantly increased blood RBC, Hb, compared with the model group has statistically significant difference (P <), but the difference between the two groups was not significant (P> ); benazepril group compared with the model group was no significant difference (P> ). 5. Pathologic changes, acceptance of renal rat subtotal excision were visible matrix hyperplasia, glomerular sclerosis, but the model group compared to the treatment group significantly lesser degree of glomerular sclerosis, one of traditional Chinese and western medicine to renal small ball for the lightest sclerosis; Immunohistochemistry results showed that the treatment group in renal tissue expression of TGF-β1 were significantly lower than model group (P <), and traditional Chinese and western medicine group can reduce the TGF-B1 in renal tissue Expression, and traditional Chinese medicine group and the benazepril group has statistically significant difference (P <). Conclusion: Yishen soup through Yiqi Jianpi, huoxuehuayu, dampness Xiexin Turbidimetry, CRF can reduce blood BUN, Scr, improve anemia and reduce proteinuria, can be reduced effectively with 5 / 6 nephrectomy-induced CRF rat kidney tissue expression of TGF-β1, thereby reducing the accumulation of ECM, slowing the development of renal fibrosis, and delay the progress of CRF. Fully Yishen soup has a good anti-renal fibrosis, but also after the United benazepril better efficacy.
Objective To evaluate acute and long2term angiographic and clinical outcomes of longstent or multiple overlapped stents (length ≥ 20 mm) implantation for diffuse atherosclerosis lesions inoctogenarians. Methods Long stent or multiple overlapped stents implantation was performed on 111diffuse native coronary lesions ( Group O : 47 lesions in 44 octogenarians ; Group Y: 64 lesions in 58 patientsaged under 60) . Baseline demographic , lesion characteristic , angiographic and procedural details weresimilar in these 2 groups. Six2month clinical and angiographic follow2up was completed in all cases. In2hospital and long2term outcomes were evaluated. Results Procedure success was 100 %for both had in2hospital major adverse cardiac events (MACE) . There was no significant difference inangiographic binary restenosis ( ≥50 % diameter stenosis) rate between the groups at follow2up ( Group Ovs. Group Y, 1218 % vs1 1019 % at 32month , 2918 % vs. 2616 % at 62month , P > 0105) . The rates oftarget lesion revascularization and MACE at follow2up were less in Group Y, but it showed no statisticalsignificance (718 % vs. 1016 % and 816 % vs. 1114 % at 32month , 1516 % vs. 2314 % and 2017 % % at 62month , respectively , P > 0105) . Conclusions Long stent implantation for diffuse lesionsin octogenarians appears safe and feasible , with high procedural success and favorable long2term outcomes.
血糖升高对出血性脑卒中（hemorrhagic apoplexy）的发生发展有极其重要的影响，不但作为重要危险因素参与HA的起始，导致疾病发病率增高，而且对HA发生后病理过程有促进作用，使血肿体积扩大，加重水肿，加重功能损害，影响预后。Hyperglycemia has a very important impact on the occurrence and development of hemorrhagic stroke (hemorrhagic apoplexy). It not only acts as an important risk factor in the initiation of HA, but also increases the incidence of disease, and promotes the pathological process of HA, enlarges the volume of hematoma, aggravates edema, aggravates functional damage, and affects prognosis.高血糖参与HA的发生机制是多方面的，包括:脂代谢异常、颈动脉重塑、内皮功能障碍、血小板功能异常、高凝状态、胰岛素抵抗。而高血糖扩大梗死面积，促进HA发展主要与致酸中毒、缺血损伤区域细胞凋亡等机制有关。Hyperglycemia is involved in the pathogenesis of HA in many aspects, including: abnormal lipid metabolism, Carotid Remodeling, endothelial dysfunction, platelet dysfunction, hypercoagulability, insulin resistance. However, hyperglycemia can enlarge the infarct area and promote the development of HA, which is mainly related to the mechanism of acidosis and apoptosis in ischemic injury area.血管内皮生长因子（VEGF）和环氧合酶（COX-2）与脑血管病的关系，已引起人们的重视。血管内皮生长因子的突出作用是诱导体内血管形成，提高血管通透性；近年来发现它也有刺激神经元、胶质细胞、轴突的生长和成活的作用。环氧合酶(cyclooxygenase，COX)，是催化花生四烯酸(arachidonic acid，AA)合成前列腺素(prostgalandin，PG)以及血栓素(thromboxan，TX)的限速酶。其中COX-1为结构型，存在于大多数组织中，催化生成维持正常结构的PG；COX-2为诱导型，在生理状态下，COX-2在大多数组织中以极低拷贝数表达。但IL-1、TNF等许多炎症刺激因子均可诱导COX-2表达。但目前有关血管内皮生长因子和环氧合酶的研究多集中在与脑缺血的关系上，而关于脑出血后脑水肿的动态变化与VEGF、COX-2表达的相关性研究却不多。The relationship between vascular endothelial growth factor (VEGF) and cyclooxygenase (COX-2) and cerebrovascular diseases has attracted people's attention. In recent years, it has been found that vascular endothelial growth factor can stimulate the growth and survival of neurons, glial cells and axons. Cyclooxygenase (COX) is a rate limiting enzyme that catalyzes the synthesis of prostaglandin (PG) and thromboxane (TX) from arachidonic acid (AA). COX-1 is a structural type, which exists in most tissues and catalyzes the generation of PG maintaining normal structure; COX-2 is an inducible type, which is expressed in a very low copy number in most tissues under physiological conditions. But many inflammatory factors such as IL-1 and TNF can induce COX-2 expression. However, at present, the researches on VEGF and COX-2 are mostly focused on the relationship with cerebral ischemia, but few on the relationship between the dynamic changes of brain edema and the expression of VEGF and COX-2 after cerebral hemorrhage.在认识到高血糖对脑出血损伤危害性同时，控制血糖水平治疗即成为脑血管病治疗手段之一，特别是采用胰岛素降低血糖水平纳入急性脑卒中治疗指南。已有研究发现胰岛素对急性期脑出血周围脑组织的缺血性损伤有保护作用。可能机制为：现已发现脑中存在胰岛素受体，胰岛素可与胰岛素受体结合，降低脑细胞对糖的摄取，从而降低脑细胞内糖的储存，减少乳酸产生的底物，从根本上纠正细胞酸中毒；同时胰岛素还可以降低外周血糖浓度，增加出血周围水肿带的有效血供，造成相对低血糖高灌流状态，从而对脑损害产生改善作用。In recognition of the harm of hyperglycemia to cerebral hemorrhage, the control of blood glucose level has become one of the treatment methods of cerebrovascular disease, especially the use of insulin to reduce blood glucose level has been included in the treatment guidelines of acute stroke. It has been found that insulin has a protective effect on the ischemic injury of brain tissue around acute cerebral hemorrhage. The possible mechanisms are as follows: it has been found that there is insulin receptor in the brain, insulin can combine with insulin receptor, reduce the uptake of sugar by brain cells, thus reduce the storage of sugar in brain cells, reduce the substrate produced by lactic acid, fundamentally correct cell acidosis; at the same time, insulin can also reduce the concentration of peripheral blood sugar, increase the effective blood supply of edema zone around hemorrhage, resulting in relatively low blood supply Hyperperfusion of blood glucose can improve brain damage.为了解这两种细胞因子与糖尿病合并脑出血损伤的关系，本研究在糖尿病模型的基础上，拟通过自体血注入法建立稳定的大鼠脑出血的动物模型，在此基础上动态观察脑出血后行为学和脑含水量的变化趋势，分析VEGF和COX-2在出血后脑组织中的分布特点和表达变化，进而探讨VEGF和COX-2在脑出血后脑组织损伤中的作用和意义，对比糖尿病大鼠和正常血糖大鼠脑水肿体积的差别，初步观察此二因子在糖尿病大鼠和正常血糖大鼠脑出血表达的差异，以期为脑出血的治疗提供新的方法和思路。In order to understand the relationship between these two cytokines and the injury of cerebral hemorrhage in diabetes mellitus, this study is to establish a stable animal model of cerebral hemorrhage by autogenous blood injection on the basis of diabetes model. On this basis, dynamic observation of the change trend of behavior and brain water content after cerebral hemorrhage is made, and the distribution characteristics and expression changes of VEGF and COX-2 in brain tissue after hemorrhage are analyzed, Furthermore, to explore the role and significance of VEGF and COX-2 in brain tissue injury after cerebral hemorrhage, to compare the difference of brain edema volume between diabetic rats and normal glucose rats, and to preliminarily observe the difference of expression of VEGF and COX-2 in cerebral hemorrhage between diabetic rats and normal glucose rats, in order to provide new methods and ideas for the treatment of cerebral hemorrhage.材料与方法Materials and methods1. 实验动物和分组1. Experimental animals and groups健康成年雄性Wistar大鼠，共96只，体重250~280克，由郑州大学实验动物中心提供。按照随机化的原则将实验动物分为4组，即假手术组、正常血糖组、高血糖组和胰岛素干预组。每组均设4个时间点：6h、24h、72h、7d。每个时间点设6只大鼠。96 healthy adult male Wistar rats weighing 250-280 g were provided by the experimental animal center of Zhengzhou University. According to the principle of randomization, the experimental animals were divided into four groups: sham operation group, normal blood glucose group, hyperglycemia group and insulin intervention group. Each group had four time points: 6h, 24h, 72h, 7d. Six rats were set at each time . 高血糖大鼠模型制作及胰岛素干预方法2. Establishment of hyperglycemia rat model and insulin intervention参照STZ诱导法制备高血糖大鼠模型。以STZ 60mg/kg，对高血糖及胰岛素干预组大鼠单次腹腔注射。大鼠正常血糖值为4一6mmol/L，注射后一周检测血糖≥为成功模型备选用。高血糖模型成功后，予干预组大鼠普通胰岛素，腹壁皮下注射，3次/d，4U/次，连用3天，测血糖值达正常范围。The hyperglycemia rat model was established by STZ induction. STZ (60 mg / kg) was used for single intraperitoneal injection in the hyperglycemia and insulin intervention group. The normal blood glucose value of rats was 4-6mmol / L, and the blood glucose ≥ was detected one week after injection as the successful model. After the success of hyperglycemia model, rats in the intervention group were given insulin, subcutaneous injection of abdominal wall, 3 times a day, 4U a time, for 3 days, and the blood glucose value reached the normal range.（论文翻译由学术堂提供）
医学论文翻译挺难的，没有一点的水平完全翻译不过来，建议还是找机构，让清北医学翻译帮忙把。
对于不少医学工作者来说，发表医学论文其中一个难题就是翻译。由于英文水平的不足，医学工作者在翻译过程中常常遇到困境。今天我们就来谈谈医学论文翻译技巧，希望对各位同学有所启发。 一、时态问题 1、表达目的所用的时态 在医学论文中，“目的”通常指进行某项研究的原因、意图，即表明研究的目标。由于研究目标的制定通常在着手开始研究之前，故可使用过去时态；但是，在论文写作中，也通常使用一般现在时来表达目的，以表达研究目的是合理的、可重复等意义。 2、表达方法和结果所用的时态 在研究性论文中，在描述所使用的实验方法、技术时通常使用过去时，以表达相关的实验方法步骤发生在过去；对结果的报道也使用过去时，以表示已经得出了结果。 3、表达结论所用的时态 医学论文的结论部分为作者表达观点、意见，以及对研究进行总结的地方，常用时态为一般现在时，以表示研究结果的客观性，如果用一般过去时，则表示这一结论仅仅适用于该研究过程中特定的情况，不具有普遍性。 二、词首字母大小写问题 关于地名和地理学术语如何正确大写的问题。因为中文不牵涉大写问题，所以中文母语的作者可能会有点迷惑。其实大写问题对于英语母语的作者而言也不太容易理顺。 三、标点符号问题 由于语言习惯影响，不少医学工作者会错误的使用英文标点符号，导致医学论文出现语言问题。下面我们列举几个英文标点符号常见的错误。 1.顿号使用错误 由于英文中没有顿号，但有些作者由于习惯影响，会在句子中使用顿号，如错误例子：The five concentrations of nitrogen in our study were 1、5、10、50、100 mg/L,respectively. 该句作者使用顿号隔开数字，应改为逗号，在英文学术论文写作中，无论是多个并行的数字、单词和短语都是用逗号来分隔。 2.书名号使用错误 对于书名、刊物名、影片、文章名在中文表达中使用书名号无可厚非，但用英文标点符号时可就注意了，如错误例子： In the book 《Pipeline Risk Management Manual》, the authorMuhlbauer W Kenr (.) grouped pipeline risk into 4 classes. 该作者错误的将句子中的书名使用了中文的标点符号，由于英文标点符号没有书名号，所以通常使用斜体字来表示，有时也可用引号、全部大写或在书刊名下划线来表示。 3.方括号和圆括号使用错误 方括号与圆括号并用时，容易产生错误，首先举一个错误的例子：[That was the colour (blue) she preferred] ，事实上在方括号和圆括号并用时，英文句子的使用方式与中文恰恰相反，即圆括号在内外，方括号在内，因此上句应改为： ( That was the colour [blue] she preferred. )
靠谱的就是用着还行的，这都是个人感受，我觉得清北医学翻译不错。
sci医学论文翻译<意得辑>学术翻译润色双重保障.sci医学论文翻译意得辑学术翻译公司,中英翻译+英文润色双重保障.5轮翻译润色流程,sci医学论文翻译作者与译者无限次沟通,直到译文达到您的要求.
医学背景知识、医学专业英语、CATTI 二级口笔译证书
靠谱的就是用着还行的，这都是个人感受，我觉得清北医学翻译不错。
英语专业专八是必须的，或者医药专业如临床医学|药学|生物医药等专业英语六级以上，这是基本的入门级门槛。
1、其他就是多加练习，增加翻译临床、药学综合类文件、法律法规、注册类文件、PPT类文件、方案说明、文献等中、英互译的经验。
2、想成为一名资深的医学翻译，可以进入像华也国际、康茂峰、RWS这种专注医学翻译业内知名的大公司，借助CAT翻译平台的翻译单元提升自己。
3、医药翻译的专业性非常强，但国内其实没有专门的医药翻译证书，很多人去考了CATTI笔译证书，但这个考试内容更偏向政经类，对医药专业性的考查没那么高，并不是必需的证书，当然有CATTI是最好的，毕竟是一个直观的实力证明，也是面试时的谈资。
4、市场上对医药翻译的需求是非常高的，一般有翻译公司经验，或者面试的试译稿做的好都有机会录用，英专生需要有专八证书，非英专生（临床医学、药学、生物、护理等专业）需要有大学英语6级证书或雅思成绩也是可以的。
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2017年被国际权威机构CSA评定为全球百强语言服务商(全球排名第74)。深耕医学领域近二十年，处理经验累计超100亿字，我们始终不忘初心，致力于打造中国领先的医学翻译品牌，择一事，终一生，为客户提供最优质的语言翻译服务。
译国译民集团拥有专业的医学文献翻译组，主攻翻译，近20年行业经验，翻译质量更有保障；企业客户合作多，各类医学稿件均有钻研，十分了解医学研究情况；业务人员直接对接，以客户为中心，具有人文关怀。专而精，只做医学类论文翻译，一个领域做到极致。
随着医学领域的不断发展和全球化进程的加速，国际合作和交流已日益成为医学研究中不可或缺的部分。在这种情况下，医学文献翻译公司的服务需求也逐渐增长。然而，市面上的医学文献翻译公司形形色色，如何选择一家优秀的翻译公司成为了许多研究人员亟待解决的问题。作为一个从业多年的医学翻译人员，我认为最好的医学文献翻译公司应该有以下特点：专业性医学文献翻译需要对医学领域有深刻的认知，对医学术语、专业文献格式等有着熟练的掌握。因此，专业性是选择医学文献翻译公司时必须考虑的关键因素。优秀的医学文献翻译公司应该拥有一支较为专业的医学翻译队伍，并且能够根据客户需求提供不同专业领域的翻译服务。质量保证医学文献翻译的质量关系到翻译结果的准确性和可读性，也直接影响到客户的学术声誉。因此，一家优秀的医学文献翻译公司应该具备一定的质量保证措施，如充分了解研究内容、严格校对工作、定期召开讨论会等等，以确保翻译品质达到高水平。保密性医学文献翻译涉及着客户的机密信息，因此保密性十分重要。优秀的医学文献翻译公司应该有完善的保密制度和措施，如签署保密协议、加密文件传送、为员工进行保密教育等等，以保护客户的商业机密和个人隐私。交付时间医学文献翻译的需求常常具有紧急性，因此交付时间也成为选择医学文献翻译公司时必须考虑的因素之一。优秀的医学文献翻译公司应该有较高的工作效率和快速的反应能力，且能够根据客户的需求提供定制化的服务。基于以上考量因素，笔者认为湖南雅言翻译公司是一家优秀的医学文献翻译公司。下面分别从四个方面介绍其优点：专业性拥有多年的医学翻译经验，在医学、生物医学工程、中药学等领域翻译服务上有着良好的口碑。公司拥有一支来自不同国家的专业医学翻译人员和行业专家，能够提供高质量的翻译服务。质量保证采用多校对制度，通过逐字逐句地校对翻译稿件，以确保翻译结果的准确性和可读性。公司定期组织内部培训和交流，不断提升翻译团队的专业水平和素质，以保证翻译品质达到高水平。保密性高度重视客户隐私和商业机密，签署严格保密协议以确保客户的信息得到妥善保管。公司还配备了专门的信息安全部门，采用多项技术措施确保客户数据的安全。交付时间能够提供快速的翻译服务，且能够根据客户的需求制定相应的翻译方案和交付时间表。在紧急情况下，公司还提供24小时在线咨询与服务。总之，作为一家专业可靠的医学文献翻译公司，具有丰富的医学翻译经验、严格的质量保证体系、保密性强以及快速高效的交付服务，能够为客户提供优质的医学文献翻译服务。
看期刊的级别吧，有的期刊是必须要求有英文摘要的，如论著栏目和论著性质的文章是必须有的。像一般的栏目没有也可。有英摘会提高论文整理的档次的！
不是你那么说的 发表我帮你
如果要翻译SCI文稿，还是建议找学术翻译公司会比较放心，比如清北医学翻译，希望对您有帮助。
建议editsprings，觉得还是可以的。
靠谱的就是用着还行的，这都是个人感受，我觉得清北医学翻译不错。
推荐editsprings，我周围人都用过，觉得不错。
我们实验室找的清北医学翻译，基本上没有啥语言问题，只有一次审稿人提出语言问题，他们服务态度挺好，免费修改了，说如果再有语言问题，终身负责，这才是良心服务啊！最后发了篇3分多的。
医学论文润色的话，建议你去找清北医学翻译，你这篇医学论文找他们在合适不过了