The purpose of Natural Medicinal ChemistryFrom natural medicines in the research and development of new drugs (including the lead compound of structure modification and transformation, the total synthesis), which our study of natural medicines are the main purpose of the chemical. Pure compounds to develop new drugs is very difficult, long cycle and the high cost of chemotherapy side effects, and easy to produce drug resistance, cause injury to human health, and from green plant life of the natural active ingredients often have high security, so to natural medicine as raw materials of drugs and drug extracts in the world is increasingly popular(1) a wide range of natural products, novel structure, pharmacological screening of the hit rate than the high synthetic compounds derived from natural lead compounds promising treatment for difficult cases of new drugs, so drugs from the natural development of new drugs has become a Top research directions. It was predicted that the future of natural drugs and chemical substances will be evenly divided, and biology were the three drugs with a tendency(2) A number of natural active compounds, because there are some defects, such as efficacy is not satisfactory, or side effects must exist, or because the content is too low, shortage of resources, it is difficult to Medium derived from natural raw materials, or because the structure was too complex, synthetic is also very difficult, so there is no direct the development and utilization of their own future. However, the natural active ingredients for the lead compounds, structural modification or structural alteration, and eventually developed into new drugs. For example: synthetic morphine substitutes - is scheduled for piperaquine (meperidine), morphine is retained in the structural parts of an effective (analgesic effect of the same!), And its addictive than morphine decreased. Another example: the active ingredient in coca leaves cocaine has a very strong narcotic effect, but toxic, easy to addiction, through research design and synthesis of local anesthetics such as procaine. Again Example: to extract from the Artemisia annua with the separation of anti-malarial activity of artemisinin, is a heat-labile compounds, such as its hydrogenated, methylated derivatives artemether made after the markedly improved stability, anti - more enhanced malaria activity. 问题补充的翻译:In the 21st century, "return to nature" of the world trend, the traditional medicine once again full of great vitality and show broad prospects for development. Western medicine sector has changed the original opinion, interested in Chinese medicine to Chinese medicine in Japan, Germany, the United States and other Western developed countries has been given scant attention Association of Traditional Chinese Medicine in 1994, set up in Los Angeles, the West has also opened a number of institutions of higher learning professional courses on Chinese medicine or the establishment of a Chinese medicine research center. The United States Food and Drug Administration (FDA) have begun to formally accept the traditional Chinese medicine compound products. This trend of Chinese medicine into the world to provide an unprecedented good opportunity. Modernization of Traditional Chinese Medicine is the inevitable trend of the modernization of Chinese medicine must be to the world and the benefit of mankind. The development of Chinese medicine is the medicine our country in the competition to win one of the effective ways.