
1. Shu HB, Agranoff A, Nabel EG, Leung K, Neish AS, Collins , Nabel GJ* (1993). Differential regulation of VCAM-1 gene expression by specific NF-kB subunits in endothelial and epithelial cells. Mol Cell Biol 13:6283-6289.2. Shu HB, Li Z, Palacios MJ, Li Q, Joshi HC* (1995). A transient association of g-tubulin at the midbody is required for the completion of cytokinesis during the mammalian cell division. J Cell Sci 108: 2955-2962.3. Shu HB , Joshi HC* (1995). g-Tubulin can both neacleate microtubule assembly and self-assemble into tubular structures in mammalian cells. J Cell Biol 130:1137-1147.4.Hsu H, Shu HB, Pan MG, Goeddel DV* (1996). TRADD-TRAF2 and TRADD-FADD interactionss define two distinct TNF receptor-1 signal transduction pathways. Cell 84:299-308.5.Shu HB, Takeuchi M, Goeddel DV* (1996). The TNF receptor 2 signal transducers TRAF2 and c-IAP1 are components of the TNF receptor 1 signaling complex.P Natl Acad Sci USA 93:13973-13978.6. Shu HB, Halpins DR, Goeddel DV* (1997). Casper is a FADD and Caspase-related Inducer of Apoptosis. Immunity 6:751-763.7.Yeh WC, Pompa JL, McCurrach ME, Shu HB, Elia AJ, Shahinian A, Ng M, Wajegam A, Mithchell K, El-Deiry WS, Lowe SW, Goeddel DV M,ak TW* (1998). FADD: essential for embryonic development and signaling from some, but not all, inducers of apoptosis. Science 279:1954-1958.8.Shu HB*, Hu WH, Johnson H (1999). TALL-1 is a novel member of the TNF family that is downregulated by mitogens. J Leukocyte Biol 65:680-683.9.Hu WH, Johnson H, Shu HB* (1999). TRAIL signal NF-kB and JNK activation and apoptosis through distinct pathways. J Biol Chem 274:30603-30610.10.Hu WH, Johnson H, Shu HB* (2000). Activation of NF-kB by FADD, Casper and Caspase-8. J Biol Chem 275:10838-10844.11.Shu HB*, Johnson H (2000). BCMA is a receptor for the TNF family member TALL-1. P Natl Acad Sci USA 97:9156-9161.12.Chen D, Li X, Zhai Z, Shu HB* (2002). A novel zinc finger protein interacts with RIP and inhibits TNF- and IL-1-induced NF-kB activation. J Biol Chem. 277:15985-15991.13.Liu Y, Xu L, Opalka N, Kappler J, Shu HB, Zhang G* (2002). Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands. Cell 108: 383-394.14.Wu M, Xu L, Li X, Zhai Z , Shu HB* (2002). AMID, an AIF homologous mitochondrion-associated protein, induces caspase-independent apoptosis. J Biol Chem 277:25617-25623.15.Xu L, Shu HB* (2002). TRAF3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kB activation and IL10 production. J Immunol 169: 6883-6889. 16.Chen D, Xu LG, Chen L, Li L, Zhai Z, and Shu HB* (2003). NIK is a component of the EGF/Heregulin receptor signaling complex. Oncogene 22:4348-4355.17.Wu M, Xu L, Zhai Z, Shu HB*(2003). SINK: a p65-interacting protein that negatively regulates NF-kB-dependent transcription. J Biol Chem 278:27072-27079.18.Bin L, Xu L, Shu HB* (2003). TIRP: a novel TIR domain-containing adapter protein involved in toll/interleukin-1 receptor signaling. J Biol Chem 27:24526-24532.19. Bin L, Nielson LD, Liu X, Mason RJ, Shu HB* (2003). Identification of UGRP1 and MARCO as a lung-specific ligand-receptor pair. J Immunol 171:924-930.20.Zhang J, Xu LG, Han KJ, Shu HB* (2004). Identification of a ZU5 and death domain containing inhibitor of NF-kB.J Biol Chem 279:17819-17825.21.Han KJ, Su X, Xu LG, Bin LH, Zhang J, Shu HB* (2004). Mechanisms of TRIF-induced ISRE and NF-kappa B activation and apoptosis pathways.J Biol Chem 279:15652-15661.22.Huang J, Teng L, Li L, Liu T, Li L, Chen D, Xu LG, Zhai Z, Shu HB* (2004). ZNF216 is an A20-like and IKKgamma -interacting inhibitor of NF-kappa B activation. J Biol Chem 279:16847-16853. 23.Xu LG, Li LY, Shu HB* (2004). TRAF7 potentiates MEKK3-induced AP1 and CHOP activation and induces apoptosis. J Biol Chem 279:17278-17282.24.Wu M, Xu LG, Su T, Huang J, Zhai Z, Shu HB* (2004). AMID is a p53-inducible gene down-regulated in tumors. Oncogene 23:6815-6819.25.Li L, Bin LH, Li F, Liu Y, Chen D, Zhai Z, Shu HB* (2005). TRIP6 is a RIP2-associated common signaling component of multiple NF-kB activation pathways. J Cell Sci 118:555-563.26.Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB* (2005). VISA is an adapter protein required for virus-triggered signaling. Mol Cell 19:727-740.27.Huang J, Liu T, Chen D, Zhai Z, Shu HB* (2005). SIKE is an IKK-relative kinases-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways. EMBO J 24:4018-4028.28.Zha J, Han K, Xu LG, Zhou Q, Chen D, Zhai Z, Shu HB* (2006). The Ret finger protein inhibits signaling mediated by the noncanonical and canonical IKK family members. J Immunol 176:1072-1080.29.Tian Y, Zhang Y, Zhong B, Wang YY, Diao FC, Wang RP, Zhang M, Chen DY, Zhai ZH, Shu HB* (2007). RBCK1 negatively regulates tumor necrosis factor- and interleukin-1-triggered NF-kappaB activation by targeting TAB2/3 for degradation. J Biol Chem 282:16776-16782.30.Diao F, Li S, Tian Y, Zhang M, Xu LG, Zhang Y, Wang RP, Chen D, Zhai Z, Zhong B, Tien P, Shu HB* (2007). Negative regulation of MDA5- but not RIG-I-mediated innate antiviral signaling by the dihydroxyacetone kinase. P Natl Acad Sci USA 104:11706-11711.31. Zhang M, Tian Y, Wang RP, Gao D, Zhang Y, Diao FC, Chen DY, Zhai ZH, Shu HB* (2008). Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3. Cell Res 18:1096-1014.32.Zhang B, Huang J, Li HL, Liu T, Wang YY, Waterman P, Mao AP, Xu LG, Zhai Z, Liu D, Marrack P, Shu HB* (2008). GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. Cell Res 18:900-910.33.Zhong B, Yang Y, Li S, Wang YY, Li Y, Diao F, Lei C, He X, Zhang L, Tien P, Shu HB* (2008). The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation.Immunity 29:538-550.34.Zhong B, Zhang L, Lei Z, Li Y, Mao AP, Yang Y, Wang YY, Zhang XL, Shu HB* (2009). RNF5 negatively regulates virus-induced IRF3 activation via ubiquitination and degradation of MITA. Immunity 30:397-407.35.Li Y, Li C, Xue P, Zhong B, Mao AP, Ran Y, Chen H, Wang YY, Yang F,Shu HB* (2009). ISG56 is a negative feedback regulator of virus-triggered signaling and cellular antiviral response. P Natl Acad Sci USA 106:7945-7950.36.Wang YY, Liu LJ, Zhong B, Liu TT, Li Y, Yang Y, Ran Yong, Li S, Tien P, Shu HB* (2010). WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kB activation. P Natl Acad Sci USA 107:815-820.37.Li S, Zheng H, Mao AP, Zhong B, Li Y, Liu Y, Gao Y, Ran Y, Tien P, Shu, HB* (2010). Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.J Biol Chem 285:4291-4297.38.Mao AP, Li S, Zhong B, Li Y, Yan J, Li Q, Teng C, Shu HB* (2010). Virus-triggered ubiquitination of TRAF3/6 by cIAP1/2 is essential for induction of interferon-beta (IFN-beta) and cellular antiviral response.J Biol Chem 285:9470-9476.39.Han KJ, Yang Y, Xu LG, Shu HB* (2010). Analysis of a TIR-less splice variant of TRIF reveals an unexpected mechanism of TLR3-mediated signaling. J Biol Chem 285:12543-12550.40.Chen R, Zhang L, Zhong B, Tan B, Liu Y, Shu HB* (2010). The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling. Cell Res 20:802-811.41. Zhong B, Zhang Y, Tan B, Liu TT, Wang YY, Shu HB* (2010). The E3 ubiquitin ligase RNF5 targets virus-induced signaling adaptor for ubiquitination and degradation. J Immunol 184:6249-6255.42.Lei CQ, Zhong B, Zhang Y, Zhang J, Shu HB* (2010). GSK3b regulates virus-triggered IRF3 activation and cellular antiviral response by promoting TBK1 activation.Immunity 33:878-889.43.Li Q, Yan J, Mao AP, Li C, Ran Y, Shu HB*, Wang YY* (2011). Tripartite motif 8 (TRIM8) modulates TNFa- and IL-1b-triggered NF-kB activation by targeting TAK1 for K63-linked polyubiquitination. P Natl Acad Sci USA 108:19341-19346.44.Ran Y, Liu TT, Zhou Q, Li S, Mao AP, Li Y, Liu LJ, Cheng JK, Shu HB* (2011). SENP2 negatively regulates cellular antiviral response by deSUMOylating IRF3 and conditioning it for ubiquitination and degradation. J Mol Cell Biol 2:283-292.45.Liu Y, Song R, Gao Y, Li Y, Wang S, Liu HY, Wang Y, Hu YH, Shu HB*(2012). Protein kinase C-δ negatively regulates T cell receptor-induced NF-kB activation by inhibiting the assembly of CARMA1 signalosome. J Biol Chem 287:20081-20087.46.He X, Li Y, Li C, Liu LJ, Zhang XD, Liu Y, Shu HB* (2012).USP2a negatively regulates IL-1β- and virus-induced NF-κB activation by deubiquitinating TRAF6. J Mol Cell Biol 5:39-47.47.Zhang J, Hu MM, Wang YY, Shu HB*(2012). TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination. J Biol Chem 287:28646-28655.48. Li Y, Chen R, Zhou Q, Xu Z, Li C, Wang S, Mao A, Zhang X, He W, Shu HB*(2012). LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection.P Natl Acad Sci USA 109:11770-11775.49.Wang YY*, Ran Y, Shu HB*(2012).Linear ubiquitination of NEMO brakes the antiviral response.Cell Host Microbe 12:129-131.50.Chen R, Li M, Zhang Y, Zhou Q, Shu HB*(2012). The E3 ubiquitin ligase MARCH8 negatively regulates IL-1β-induced NF-κB activation by targeting the IL1RAP coreceptor for ubiquitination and degradation. P Natl Acad Sci USA 109:14128-14133.51.Zheng H, Li Q, Chen R, Zhang J, Ran Y, He X, Li S, Shu HB* (2012).Dual-specificity phosphatase 14 (DUSP14) negatively regulates TNF-a and IL-1-induced NF-κB activation by dephosphorylating the protein kinase TAK1. J Biol Chem 288:819-825.52.Yang Y, Liao B, Wang S, Jin Y, Shu HB*, Wang YY*. (2013). The E3 ubiquitin ligase WWP2 negatively regulates TLR3-mediated innate immune response by targeting TRIF for ubiquitination and degradation.PNAS 110(13):5115-20.53.Li C, Wei J, Li Y, He X, Zhou Q, Yan J, Zhang J, Liu Y, Liu Y, Shu HB* (2013). Transmembrane protein 214 (TMEM214) mediates endoplasmic reticulum stress-induced caspase-4 activation and apoptosis.J Biol Chem54. Lei CQ, Zhang Y, Xia T, Jiang LQ, Zhong B, Shu HB* (2013). FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3. J Biol Chem 288:12596-12604.55.Chen H, Li Y, Zhang J, Ran Y, Wei J, Yang Y, Shu HB* (2013). RAVER1 is a coactivator of MDA5-mediated cellular antiviral response.J Mol Cell Biol 5:111-119.发表著作舒红兵 主编,《抗病毒天然免疫》,科学出版社,北京,2009。
要想知道舒红兵事件是怎么一回事,大家是不是应该先来了解了解舒红兵是谁啊,这位可不是一般角色,作为国内著名的科学家,他在专业领域上都做过什么样突出的贡献其实才是大家应该来关注的重点,对于这种科研工作者大家不能总是关注人家的私人生活,多把注意力和精力放到工作事业上来,不要三天两头的去好奇别人的私生活,人家的生活和别人有什么关系呢?在这方面还是不要有太重的好奇心了。
舒红兵
舒红兵是1967年1月出生重庆市荣昌县的教育科研工作者,他有细胞生物学家、免疫学家,中国科学院院士,发展中国家科学院院士,武汉大学副校长、医学研究院院长、教授多个头衔,这些头衔都能证明舒红兵不是一个简单任务,先后毕业于兰州大学的他后又取得中国医学科学院基础医学研究所硕士学位,到了1995年获得美国埃默里大学博士学位,2011年当选为中国科学院院士,一年后成为发展中国家科学院院士。
在学术领域上,舒红兵主要从事免疫相关的细胞信号转导研究,他在抗病毒天然免疫反应等领域取得了一系列有重要国际影响的成果。最近大家不是被各种新冠病毒闹得人心惶惶么,现在虽然疫情已经被遏制住了,但最关键的还是需要拿出疫苗才行,否则就算我们国家暂时控制住了疫情,没有疫苗还是会感觉到担忧,舒红兵等人所从事的工作就是研究各类病毒疫苗的。
舒红兵
此前舒红兵曾发现了多个在病毒感染诱导细胞表达I型干扰素的过程中发挥关键作用的信号蛋白,为了解细胞抗病毒反应的分子机制做出了重要贡献,同时他还发现了多个负调控I型干扰素过量表达的蛋白和作用机制,这种精细调控机制避免机体产生过激的免疫反应;发现了新的肿瘤坏死因子家族成员,阐述了肿瘤坏死因子家族的多个成员信号转导的早期分子事件,这都为了解相关免疫疾病的分子机制做出了贡献。
舒红兵的学术著作有2009年出版的《抗病毒天然免疫》和2015年出版的《中国学科发展战略·免疫学》,至于论文方面,据2020年3月武汉大学医学研究院官网显示,舒红兵先后在国际刊物发表论文160篇,被SCI引用12000余次,其中通讯作者论文单篇最高被引用1200余次,第一作者论文单篇最高被引用350余次。中国科学院评价舒红兵时说他为解细胞抗病毒反应、相关免疫疾病的分子机制做出了重要贡献。
舒红兵,中国科学院院士,教授,博士生导师。现任武汉大学生命科学学院院长、中国细胞生物学学会副理事长。1987年毕业于兰州大学生物学系,1990年获中国医学科学院基础医学研究所硕士学位,1995年于美国Emory大学获博士学位。2011年当选中国科学院院士。细胞生物学、免疫学专家,主要从事免疫相关的细胞信号转导研究,在抗病毒天然免疫反应等领域取得了一系列有重要国际影响的成果。发现了多个在病毒感染诱导细胞表达I型干扰素的过程中发挥关键作用的信号蛋白,为了解细胞抗病毒反应的分子机制做出了重要贡献;发现了多个负调控I型干扰素过量表达的蛋白和作用机制,这种精细调控机制避免机体产生过激的免疫反应;发现了新的肿瘤坏死因子家族成员,阐述了肿瘤坏死因子家族的多个成员信号转导的早期分子事件,为了解相关免疫疾病的分子机制做出了贡献。发表SCI论文70篇,其中以第一和通讯作者发表论文56篇,被SCI期刊他引2705次,单篇被他引120次以上的有7篇;回国工作后以通讯作者发表的25篇IF>5的论文中,包括3篇Immunity,1篇Mol. Cell,3篇PNAS,1篇EMBO J。作为主编出版专著《抗病毒天然免疫》。作为第一完成人获国家自然科学二等奖
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