In daily life, we are in contact, children from newborns to teenagers, and pediatric dose-dependence long mainly based on the pediatric weight, age, surface area or adult proportion computation, did not fully consider children each period (especially neonatal, infant) physiological characteristics and drug characteristics, so pediatric drug use is reasonable is worth attention and Drug treatment is one of the necessary means disease, but if application undeserved can cause harm to human body, especially in its growth vigorous stage in children, have a bit inadvertent might cause unnecessary So pediatric drug problem more and more attention by people, paediatric rational drug use is also more and more attention by This article from the children with special physiological structure, analyzes pharmacists in outpatient pharmacy drugs dispensed, reminding patients in drug usage, families, special storage etc dosage should pay special attention to problems, thus further ensure clinical pediatrics the rational use of drugsKeywords: pediatric and rational drug use, allocate