Reviewer #1: The manuscripts is well structured and it is supported by good quality However, before being considered for publication in this journal, the following revisions have to be addressed: The English is poor and it has to be extensively In addition, there are several typos that have to be The introduction is too generic and it has to be re-written in order to present better the importance of obtaining the presented flower-like CuO The period: 'Recently, a lot of designed artificial structures learn from nature, for living organisms, born with high level of tuning and controlling inorganic materials to produce fine morphologies or architecture with the aid of precise direction of bio-molecules, set remarkable Bio-inspired strategies with organic ligands, additives or templates are thus especially ' is not clear and it fails to increase the impact of the
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