这125个问题的前25个为： 1. What Is the Universe Made Of? 宇宙是由什么组成的？2. What is the Biological Basis of Consciousness? 意识的生理基础是什么？3. Why Do Humans Have So Few Genes? 人的基因为什么这样少？4. To What Extent Are Genetic Variation and Personal Health Linked? 基因的变异和人的健康有多大层度的联系？5. Can the Laws of Physics Be Unified? 物理学的定律可以统一吗？6. How Much Can Human Life Span Be Extended? 人的寿命可以有多长？7. What Controls Organ Regeneration? 是什么控制着器官的再生？8. How Can a Skin Cell Become a Nerve Cell? 皮肤细胞怎样成为神精细胞？9. How Does a Single Somatic Cell Become a Whole Plant? 单体细胞怎样才为全植物的？10. How Does Earth's Interior Work? 地球的内部规律是怎样的？11. Are We Alone in the Universe? 在宇宙中我们是单独的吗？12. How and Where Did Life on Earth Arise? 地球生物是怎样和在哪里起源的？13. What Determines Species Diversity? 是什么决定了物种的差异？14. What Genetic Changes Made Us Uniquely Human? 是什么基因变化使我们成了独特的人类？15. How Are Memories Stored and Retrieved? 记忆是怎样储存和提取的？16. How Did Cooperative Behavior Evolve? 合作的行为是怎样进化的？17. How Will Big Pictures Emerge from a Sea of Biological Data? 从海量的生物数据中可以看出什么？18. How Far Can We Push Chemical Self-Assembly? 在化学的自我聚合上我们能够走多远？19. What Are the Limits of Conventional Computing? 传统计算的极限在哪里？20. Can We Selectively Shut Off Immune Responses? 我们能有选择地关闭免疫反应吗？21. Do Deeper Principles Underlie Quantum Uncertainty and Nonlocality? 在量子不确定性和非定域性的下面还有更深层的原理吗？22. Is an Effective HIV Vaccine Feasible? 艾滋病可以有疫苗吗？23. How Hot Will the Greenhouse World Be? 温室世界会有多热？24. What Can Replace Cheap Oil -- and When? 什么东西可以替代廉价石油，什么时候？25. Will Malthus Continue to Be Wrong? 马尔萨斯会一直错下去吗？
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