发布时间：
并不一定。并不是所有英文医学期刊都被SCI收录了，能在SCI收录的期刊上发表的文章才是“SCI论文”。
SCI收录全世界出版的数、理、化、农、林、医、生命科学、天文、地理、环境、材料、工程技术等自然科学各学科的核心期刊约3500种。
作为一部检索工具，SCI一反其它检索工具通过主题或分类途径检索文献的常规做法，而设置了独特的“引文索引”（Citation Index）。即通过先期的文献被当前文献的引用，来说明文献之间的相关性及先前文献对当前文献的影响力。
SCI以上做法上的特点，使得SCI不仅作为一部文献检索工具使用，而且成为科研评价的一种依据。科研机构被SCI收录的论文总量，反映整个机构的科研、尤其是基础研究的水平；个人的论文被SCI收录的数量及被引用次数，反映他的研究能力与学术水平。
相关文件：
2020年2月，教育部、科技部印发了《关于规范高等学校SCI论文相关指标使用树立正确评价导向的若干意见》，该文件要破除论文“SCI至上”，也要以此为突破口，拿出针对性强、操作性强的实招硬招，破除“唯论文”，树立正确的评价导向。
以上内容参考：百度百科-科学引文索引
由于随着科技和社会的发展，人们的生活水平不断提高，当代人把身体健康看得越来越重，对自己的饮食习惯，药物的使用与滥用和急救知识等格外关注。下面是我带来的医学科普 文章 ，欢迎阅读!
医学科普文章英文版1
为什么总是睡不好?十大常见睡眠错误
Most of us have struggled at some point with sleep. Whether it’s not getting enough sleepor struggling to get up in the morning, it can be difficult to get the balance just right.
大多数人都遇到过一些睡眠问题。有可能是睡得不够，又或者是早晨起不来，很难达到平衡睡得舒服。
However, sleep is essential if we want to be productive in life. It provides us with theenergy we need to get stuff done!
然而为了保证精力充沛，睡眠是十分必要的。我们需要睡足了才有精力干活!
Here are the 10 most common sleep mistakes people make and a few tips for avoidingthem!
下面列出了常见的十大睡眠错误以及纠正小贴士。
1. The snooze button
闹钟止闹按钮
Don’t EVER hit the snoozebutton. It really is much more beneficial to just get up on yourfirst alarm. Think about it – the snooze button gives you an extra 10 minutes or so sleep. Inthe grand scheme of your day this really won’t provide you with any more energy. In-fact itdoes the opposite. Research has shown that ‘interrupted sleep’ can cause us to feel moretired.
千万不要按止闹按钮，其实在闹铃一响时就起来对身体更好。想想看，止闹按钮可以让你多睡10分钟或者更长一点时间。但相比于一整天满满的计划，这多睡的10分钟根本无法为你多添几份活力。事实上恰恰相反，研究表明受干扰的睡眠会让人更加疲倦。
2. Disorganized sleeping habits
不规律的睡眠习惯
It’s much easier to get to sleep each night (and wake up feeling refreshed) if we have aregular routine. This means going to bed at roughly the same time each night and getting upat roughly the same time each morning. If you’re disorganized with your sleeping routine, youend up interrupting your natural sleeping rhythms, which can cause insomnia and fatigue.
如果每天的作息时间规律，每晚会更加容易入眠(醒来时也会感到神清气爽)。也就是说每晚在相对固定的时间睡觉，每天早上在相对固定的时间起床。如果你睡觉的时间不规律，就会打乱你的生物钟，导致失眠和疲劳感。
3. Long naps
小睡时间过长
Long naps can disrupt your sleeping rhythms so if you’re desperate for a nap then keep itunder the 30 minute mark (and before 4pm). Short naps after lunch can help to restore energylevels (just make sure you don’t sleep in).
小睡时间过长会打乱人的生物钟，所以如果你真的很想打个盹儿的话，请把时间控制在30分钟以内(而且要在下午四点前睡)。在午餐后小睡一会儿有助于恢复体力(只是不要睡过头了)。
4. Caffeine/stimulants
咖啡因/兴奋剂
Don’t drink any caffeinated drinks after mid-day. Caffeine stimulatesyour body for up to 12hours after consumption so it’s important to restrict your intake later in the day. Be aware ofsupposed ‘herbal’ drinks such as green tea, which can have a high dose of caffeine. Alwayscheck the label.
请不要在中午之后饮用含咖啡因的饮料。咖啡因会持续的影响人体12个小时，所以要控制自己不要在中午以后摄取咖啡因。小心一些“草本”饮料，例如绿茶含有很高的咖啡因。每次喝饮料之前都要看一下成份标签。
5. Stress &negative thinking
压力和消极想法
Stress is a large reason why many people find it difficult to sleep. One of the worse thingsyou can do is be stressed before bed. Stress produces chemicals that physically stop us fromsleeping. Try and clear your mind before bed time and make an effort to think positive thoughtsthat aid sleep.
压力是造成人难以入眠的重要原因。在上床睡觉前带着太大压力就更加糟糕了。压力会使人分泌出某些从生理上阻止睡眠的化学物质。尝试在睡前清空所思所想，努力朝有助于睡眠的积极方面想吧。
6. Too much light
光线太亮
Our bodies depend on ‘sleep signals’ to fall asleep and one of those signals is sure your room is as dark as possible before trying to get to sleep. Even a thin stream oflight coming in through your window can disrupt your pinealgland’s production of sleephormones and therefore disturb your sleep rhythms, so make sure your blinds are closed!
我们的身体依靠“睡眠信号”来入睡，其中一个信号就是黑暗。所以在睡觉前要确保房间光线尽可能暗。即便是透过玻璃窗射进来的一小束光线也可能会干扰人的松果体分泌睡眠荷尔蒙，从而干扰睡眠生物钟。因此要保证关上百叶窗!
7. Sugar before bedtime
睡前摄取糖分
Sugary snacks before bedtime are a really bad idea. The sugar can disrupt the chemicals inyour body causing you to wake up during the night. Limit all late night sweet treats – if you’rehungry go for a protein based snack instead.
睡前吃含糖的零食真的是个坏主意。糖会破坏人体体内的化学物质，导致人在夜间醒来。因此要控制晚间吃甜食的量，如果你饿了，去吃一些蛋白质为主的零食吧。
8. Alcohol before bedtime
睡前喝酒
Alcohol is a sedativeand therefore people get fooled into thinking it will help them get agood nights sleep. The reality is that it may initially induce sleep, however it usually drasticallyimpairs sleep during the second half of the night which leads to interrupted sleep patterns thatwill leave you feeling fatigued in the morning (not to mention the hangover!)
酒精有镇定作用，因此人们会误以为酒精能帮助睡眠。实际上酒精可能会在一开始促进人睡眠，但是它也常会在后半夜严重影响人的睡眠，打乱人的睡眠模式，让你在早上觉得很疲乏(更不用说还有宿醉了)。
9. TV in the bedroom
卧室里摆放电视
It can be easy to fall asleep on the couch in front of the TV. It’s important we don’t try andreplicatethis strategy in the bedroom though. The bedroom must only be associated withsleep. When you start to introduce mental stimulation such as a TV this can severely disruptyour sleep patterns.
坐在电视机前的沙发上很容易睡着，但重要的是我们不能在卧室里尝试这一 方法 。卧室应当只与睡眠有关，把电视机之类刺激神经的东西放进卧室会严重打乱你的睡眠模式。
10. Worrying about sleep
担心睡眠
If you’ve had a few bad nights sleep, then the worst thing you can do is worry too muchabout it. When we place too much focus on sleeping this can cause anxiety and only make theproblem worse. Try to go with the flow and let your body naturally get into a healthy sleeppattern.
当你几天都睡不好后，最糟糕的事情就是你还总是担心自己的睡眠。当我们把注意力过多放在睡眠上时，就会导致焦虑，而焦虑只会让睡眠问题变得更严重。试着顺其自然地让身体进入健康的睡眠模式吧。
医学科普文章英文版2
5个有害健康的常见生活习惯
Everyday health hazard 1: Lying
日常健康危害之1：撒谎
Whether you’re complimenting your best friend’s unflattering hairdo or “improvising”on thecost of your new designer shoes, we all tell the odd fibfrom time to time. However, accordingto research, those little white lies could be more harmful than you think. Lying can generatefeelings of stress which are damaging to your health, and a study by researchers at theUniversity of Notre Dame found that when people reduced the amount of lies they told theysuffered from less headaches, sore throats and anxiety.
无论你是在恭维你最好朋友那不讨喜的发型，或临时冲动购物买下最新名牌鞋，在这时候我们通常会撒一些古怪的小谎。但是最新的研究显示，即便是那些无害纯洁的小谎言也会带来意想不到的危害。撒谎会产生压力，而压力会损害你的健康。一项来自圣母大学的研究发现，当人们减少说谎话的次数时，他们就会减少头疼、咽喉疼痛和焦虑的患病次数。
Everyday health hazard 2: Eating at your desk
日常健康危害之2：办公桌上吃饭
If you’re having a busy day in work, it can be tempting to skip your lunch break and eat atyour desk. However, missing out on breaks is not only bad for your stress levels, eating whiledistracted may also mean you are more likely to overeat. Furthermore, spending your lunchhour at your desk can lengthen the time you are physically inactive and also expose you toharmful bacteria. According to a study by the University of Arizona, your work station containsnearly 400 times more germs than the average toilet seat, making it a less than ideal place fordining.
如果你工作忙绿，你的午餐休息时间可能没了，就不得不在办公桌上吃午饭。然而错过了休息不仅会让你感到压力紧张，而且心烦意乱的你在这时候吃饭会导致你进食过量。此外，在办公桌上吃饭，你的身体不活动的时间就会增加，还会让你暴露在有害的细菌环境中。亚利桑那大学的研究 报告 显示，办公环境细菌量是马桶座圈平均量的400倍，你还想在这样的地方进餐吗?
Everyday health hazard 3: Housework
日常健康危害之3：家务
Need an excuse to put your feet up? Well, good news: research suggests that leaving thehousework for another day could give your health a boost! Research results published in theJournal of Family Psychology revealed that doing housework when you get home from workprevents levels of cortisol (the stress hormone) from lowering and reduces recovery fromstress. However, stress levels for both men and women were lowered by housework beingcompleted – just so long as they weren’t the ones doing it. Look after your health by takingturns to do the housework with other members of your household if possible, and take timeout to relax afterwards.
想找个理由不做家务?那有好消息了：研究显示，人们把 家务活 留到第二天做，身体会更棒!《家庭心理学》刊登了这篇研究报告，报告结果显示，当你下班回家后做家务活，皮质醇(压力荷尔蒙)的释放会被抑制。皮质醇能降低压力，还能缩短受压后的恢复时间。但是当家务被完成后，男性和女性的压力水平都会降低——只要做家务的不仅仅只有他或她。可以的话，你可以和家人分担家务，这样能让自己保持健康，还有家务过后记得要抽时间休息啊。
Everyday health hazard 4: Using cash machines
日常健康危害之4：使用自动提款机
Withdrawing money from ATM machines is a common habit for most of us. However,cleanliness tests in Britain have revealed that cash machines are just as dirty as public toilets,and many of us are failing to wash our hands after using them. Experts assessed swabs fromthe key pads on cash machines and also from nearby public toilets and found that they bothcontained the same types of bacteria known to cause sickness. To look after your health, usean antibacterialhand gel once you have made your withdrawaland after handling money.
从自动提款机中提起现金是大多数人的日常习惯。然而一项英国的洁净测试显示，提款机和公厕一样脏，而且，大多数人在使用后都不会去洗手。专家们在自动提款机的键盘和附近的公厕中提取了样品，发现两者均含有同样致病菌。为了您的健康，请在提款和处理钱款后使用抗菌洗手液清洗。
Everyday health hazard 5: Cancelling plans
日常健康危害之5：取消计划
Find yourself frequently cancelling plans and bailing out on social events to have a bit oftime to yourself? Then it may be time to pay some attention to your social life. While a bit of‘me time’ is essential to good mental and physical health, too much time on your own canactually be bad for you. Research suggests that having strong social bonds promotes brainhealth, reduces feelings of depression and stress and encourages you to look after yourhealth. In fact, a study found that having few friends affects your longevityas much as smoking15 cigarettes a day.
发现自己频繁取消计划，还想摆脱社交活动，只为挤出属于自己的空闲时间?那么现在是时候在自己的社交生活中多多用心。拥有少量属于自己的时间，对于精神和身体方面是非常有益处的，但是太多属于自己的时间，反而有可能会害了你。研究显示，较强的社交联系有益于大脑的健康，同时能避免抑郁、降低压力，还能鼓励自己多关注自身的健康。事实上一项研究发现，没有朋友也会减少你的寿命，效果相当于1天抽15根烟。
医学科普文章英文版3
睡前玩iPad会影响睡眠质量
Using tablet computers like Apple’s iPad and Samsung’s Galaxy Note just before bed can lead toa poor night’s sleep, according to research.
More and more people are taking their tablets to bed with them to surf the web, checkFacebook or email before switching off the light.
But researchers are warning that the blueish light their screens emit can stop users getting agood night’s sleep.
That is because this type of light mimics daylight, convincing the brain that it is still daytime.
Blue light suppresses production of a brain chemical called melatonin, which helps us fall is because our brains have evolved to be wakeful during daylight hours.
By contrast, light which is more orange or red in tone does not suppress melatoninproduction, perhaps because our brains recognize it as a cue that the day is ending.
Neurologists have known for years that staring at screens late in the evening can disrupt sleep- be they television screens, computer screens or mobile phone screens.
However, because mobiles and tablets are by nature portable - not to say addictive - morepeople are taking them into the bedroom.
Users also tend to hold them much closer to their eyes than a computer or television screen.
Researchers at the Lighting Research Centre, at the Rensselaer Polytechnic Institute in NewYork, are warning that looking at tablet displays for more than two hours “leads to asuppression of our natural melatonin levels as the devices emit optical radiation at shortwavelengths” - in other words, they emit bluer light.
They say: “Although turning off devices at night is the ultimate solution, it is recommendedthat if these devices are used at night displays are dimmed as much as possible and that thetime spent on them before bed should be limited.”
They drew their conclusions after measuring melatonin levels in 13 volunteers, after they hadspent time viewing iPads at full brightness at a distance of 10 inches, for two hours.
Melatonin levels were significantly lower after they had done this, than they were after thevolunteers had viewed their iPads for the same time, but while wearing orange glass goggles,which cut out the blue light.
They wrote in the journal Applied Ergonomics that tablet makers could "tune the spectral powerdistribution of self-luminous devices" so that they disrupted the sleep patterns of users less.
It is not just a good night’s sleep that could be jeopardized by too much late night screentime.
Researchers know that persistent disruption to sleep patterns can lead to an increased risk ofobesity, and even breast cancer.
However, these studies tend to be comparisons of those with chronic sleep disruption, suchas long term shift workers, with those who have normal sleep patterns.
英文医学论文都是sci么？“并不一定。并不是所有英文医学期刊都被SCI收录了,能在SCI收录的期刊上发表的文章才是“SCI论文”。”只是说他们是英文为主！
“小柯”是一个科学新闻写作机器人，由中国科学报社联合北京大学高水平科研团队研发而成，旨在帮助科学家以中文方式快速获取全球高水平英文论文发布的最新科研进展。《自然》● 科学家揭示肝硬化细胞水平发病机制英国爱丁堡大学炎症研究中心N. C. Henderson和P. Ramachandran研究组合作发现在单细胞水平上肝硬化的纤维化生态位。相关论文2019年10月9日在线发表于《自然》。为了获得细胞水平的直接相关的发病机制，并为治疗设计提供依据，他们分析了超过100,000个人类单细胞的转录组，从而得出了健康和肝硬化人类肝脏中存在的非实质细胞类型的分子定义。他们发现了一种新型的与疤痕相关的TREM2+CD9+巨噬细胞亚群，该亚群在肝纤维化中扩展，从循环单核细胞分化，并且具有促纤维化作用。他们还定义了新型ACKR1+和PLVAP+内皮细胞，它们在肝硬化中扩展，在形态构造上受疤痕限制并增强白细胞的转运。新型疤痕相关巨噬细胞，内皮细胞与PDGFRα+胶原生成间充质细胞之间相互作用的多谱系配体-受体模型揭示了包括TNFRSF12A，PDGFR和NOTCH信号传导在内的几种促纤维化途径的疤痕内活性。他们的工作在单细胞水平上剖析了未曾被预料的人体器官纤维化的细胞和分子基础，并提供了发现肝硬化合理治疗目标所需的概念框架。据悉，目前尚无有效的抗肝纤维化疗法治疗肝硬化，肝硬化是全世界的主要杀手。相关论文信息：● 研究解码胎儿肝脏造血功能剑桥大学Sam Behjati、Elisa Laurenti、Sarah A. Teichmann 和英国纽卡斯尔大学Muzlifah Haniffa研究组合作解码了人类胎儿肝脏造血功能。 这一研究成果在线发表在2019年10月9号的《自然》上。研究人员对约140,000个肝脏和74,000个皮肤以及肾脏和卵黄囊细胞进行单细胞转录组测序，确定了人类血液和免疫细胞在发育过程中的组成。研究者从造血干细胞和多能祖细胞推断分化轨迹，并评估组织微环境对血液和免疫细胞发育的影响。研究揭示了胎儿皮肤中的生理性红细胞生成以及卵黄囊中肥大细胞，自然杀伤细胞和先天性淋巴样细胞前体的存在。研究还证明了在妊娠过程中胎儿肝脏的造血成分发生了变化，其远离了主要的类红细胞，同时伴随着HSC / MPPs分化潜能的平行变化，研究人员并对此进行了功能验证。该研究揭示的胎儿肝脏造血综合图谱为研究儿科血液和免疫疾病提供了蓝图，并为HSC / MPP的治疗潜力提供了参考。研究人员表示，胎儿肝脏中的决定性造血作用支持造血干细胞和多能祖细胞的自我更新和分化，但其在人类中的作用仍然不清楚。相关论文信息：● 新发现可作为黑色素瘤潜在疗法美国西雅图福瑞德·哈金森癌症中心Robert K. Bradley小组和纽约纪念斯隆-凯特琳癌症中心Omar Abdel-Wahab小组合作，发现了癌症中剪接体内非典型BAF复合物的破坏，并基于这一机制提出了对待一类肿瘤恶化的治疗方法。 这一研究成果在线发表在2019年10月9日的《自然》上。研究人员结合泛癌剪接分析与阳性富集CRISPR筛选来优化促进肿瘤发生的拼接改变。研究团队报告说，多样的SF3B1突变集中在对BRD9的抑制上，BRD9是最近描述的非典型BAF染色质重塑复合体的核心组成部分，该复合体也包含GLTSCR1和GLTSCR1L57。突变体SF3B1识别BRD9内的异常的、深内含子分支点，从而诱导内源性逆转录病毒元件衍生的毒性外显子的包被和随后BRD9 mRNA的降解。BRD9的清除引起了CTCF相关基因座上非经典BAF的减少，并促进了黑色素瘤的发生。BRD9是葡萄膜黑色素瘤中一种强有力的抑制剂，利用反义寡核苷酸或CRISPR介导诱变在SF3B1变异细胞中纠正BRD9 的错剪接可以抑制肿瘤增长。据悉，SF3B1是癌症中最常见的突变RNA剪接因子，但对SF3B1突变促进恶性肿瘤的机制了解甚少。相关论文信息：● 癌症中U1剪接体RNA发生高频突变加拿大多伦多大学Lincoln D. Stein研究组研究显示，U1剪接体RNA在多种癌症中发生突变。该项研究成果在线发表于2019年10月9日的《自然》。他们报告了在几种肿瘤类型中，U1 snRNA的第三个碱基处高频出现的Agt;C体细胞突变。 U1的主要功能是通过碱基配对识别5C突变与肝细胞癌的酗酒和慢性淋巴细胞性白血病的侵袭性IGHV基因未突变亚型相关。U1突变还可以使CLL患者独立接受不良预后。他们的研究证明了剪接体RNA中最早的非编码驱动程序之一，揭示了癌症中异常剪接的新机制，可能代表了新的治疗靶标。他们的发现还表明，驱动程序的发现应扩展到更广泛的基因组区域。据悉，癌症是由称为驱动因子的基因组改变引起的。已知有数百种编码基因的驱动程序，但尽管进行了深入的搜索，但迄今为止仅发现了少数非编码驱动程序。最近注意力已经转移到改变的RNA剪接在癌症中的作用。尽管仅在蛋白质编码剪接因子）中发现了导致多种转录类型的异常剪接的驱动子突变，但仍在多种癌症类型中得到了证实。相比之下，由于表征非编码癌症驱动程序的综合挑战和snRNA基因的重复性，对剪接体非编码成分，一系列小核RNA的癌症相关改变的研究很少。相关论文信息：● 非编码RNA突变可引起Shh型髓母细胞瘤近日，加拿大病童医院Michael D. Taylor研究组发现复发性非编码的U1-snRNA突变驱动Shh型母细胞瘤的隐性剪接。2019年10月9日，国际知名学术期刊《自然》在线发表了这一成果。研究人员报道了约50％的Sonic hedgehog型髓母细胞瘤中U1剪接体小核RNA的高度复发性热点突变，该突变在其他髓母细胞瘤亚型中均不存在。在其他36种其他肿瘤类型的2442例癌症中，发现此U1-snRNA热点突变小于％。婴儿Shh-MB基本上不存在这种突变，这种突变发生在97％的成年人和25％的青少年中。U1-snRNA突变发生在5剪接位点结合区域，并且snRNA突变型肿瘤显著破坏RNA剪接，并带有过量的5隐性剪接事件。突变的U1-snRNA介导的可变剪接使肿瘤抑制基因失活，并激活癌基因，这是治疗的新靶点，并造成了癌症中非蛋白质编码基因的高度复发性和组织特异性突变。据介绍，癌症中的复发性体细胞单核苷酸变异很大程度上局限于蛋白质编码基因，在大多数儿童癌症中很少见。相关论文信息：《英国医学杂志》● 非酒精性脂肪肝与急性心肌梗死和卒中发病风险的相关性荷兰鹿特丹伊拉斯谟大学医学中心Naveed Sattar研究小组的一项最新研究分析了非酒精性脂肪性肝病与急性心肌梗死和卒中的发病风险的相关性。相关论文2019年10月8日在线发表于《英国医学杂志》。研究组搜集了2015年12月31日前四个欧洲国家基于人口的电子基础卫生数据库，其中意大利1542672人，荷兰2225925人，西班牙5488397人，英国12695046人。对120795名确诊为NAFLD或非酒精性脂肪性肝炎的患者平均随访了年。在校正年龄和吸烟因素后，与匹配的对照组相比，NAFLD或NASH患者的AMI风险比为，卒中的综合风险比为。而在风险因素数据更为完整的组别中，在校正收缩压、2型糖尿病、总胆固醇水平、他汀类药物使用和高血压等因素后，NAFLD或NASH患者的AMI的风险比为，卒中的风险比为。总之，对1770万例患者进行常规护理，在排除心血管危险因素后，NAFLD的诊断与AMI或卒中风险无关。NAFLD患者的成人心血管风险评估很重要，但无需以特殊方式进行。相关论文信息：● 中国科学家系统评价非小细胞肺癌一线治疗的疗效广州医科大学附属第一医院何建行教授研究组对晚期表皮生长因子受体突变的非小细胞肺癌一线治疗的疗效和安全性进行了系统评价和网络荟萃分析。这一研究成果于2019年10月7日在线发表于《英国医学杂志》。研究组在PubMed、Embase、Cochrane中央对照试验注册中心和等知名数据库中检索2019年5月20日之前符合标准的文献。入选研究均比较了晚期EGFR突变NSCLC患者一线治疗中两种以上的疗法，且至少报告以下临床结果指标之一：无进展生存、总生存、客观缓解率和3级及以上不良反应。18项符合条件的试验包括4628例患者和12种治疗方法：EGFR酪氨酸激酶抑制剂，基于培美曲塞的化疗，培美曲塞游离化疗以及联合治疗。与吉非替尼+培美曲塞化疗的疗效相当，奥希替尼显示出最有利的无进展生存期，显著优于达克替尼、阿法替尼、厄洛替尼、吉非替尼、埃克替尼、培美曲塞为基础的化疗、培美曲塞游离化疗、阿法替尼+西妥昔单抗和吉非替尼+培美曲塞。奥希替尼和吉非替尼联合以培美曲塞为基础的化疗在提供最佳总体生存效益方面也大致相当。但联合治疗引起的毒性更大，尤其是厄洛替尼+贝伐单抗，易导致3级以上的严重不良事件。不同的EGFR-TKIs显示出不同毒性谱。两种最常见的EGFR突变类型的亚组分析表明，在外显子19缺失的患者中，奥希替尼与最佳无进展生存相关，而在Leu858Arg突变患者中，吉非替尼+培美曲塞化疗与最佳无进展生存相关。总之，与其他一线治疗相比，奥希替尼和吉非替尼+培美曲塞化疗可显著提高晚期EGFR突变的NSCLC患者的无进展生存期和总生存期。对于外显子19缺失和Leu858Arg突变的患者，奥希替尼和吉非替尼+培美曲塞化疗的无进展生存最优。相关论文信息：● 慢性阻塞性肺病患者预后预测模型的系统评价希腊约阿尼纳大学医学院Evangelos Evangelou研究团队系统分析和批判评价了慢性阻塞性肺病患者预后的预测模型。这一研究成果于2019年10月4日在线发表于《英国医学杂志》。研究组系统搜索了228篇符合条件的文献，描述了408个预后模型的开发，38个模型的外部验证，以及20个针对COPD以外疾病预后模型的验证。408个预后模型建立于三个临床环境：239个针对门诊患者，155个针对住院患者，14个针对急诊患者。这408个预后模型中，最普遍的终点是死亡率、COPD急性加重和再次住院的风险。总体来说，最常用的预测因素是年龄、一秒用力呼气量、性别、体重指数和吸烟。在408个预后模型中，100个得到了内部验证，91个检测了校准开发模型。286个模型无法展示，只有56个模型可通过完整方程式展示。C统计模型可对311个模型进行判别。38个模型进行了外部验证，但其中只有12个由一个完全独立的团队进行验证。只有7个预后模型的总体偏倚风险较低。总之，该研究对COPD患者预后预测模型进行了详细的描绘和评估，发现它们的开发过程存在一些方法上的缺陷，且外部验证率较低。未来的研究应着眼于通过更新和外部验证来对现有的这些模型进行改进，并在临床实践中对它们的安全性、临床有效性和成本效益进行评估。相关论文信息：合作事宜：投稿事宜：王者之心2点击试玩
羟乙基淀粉的药代动力学较为复杂，与分子量和摩尔取代度密切相关。当静脉给予本品时，低于肾阈（60，000－70，000道尔顿）的小分子很容易通过肾脏经尿排泄，大分子羟乙基淀粉在通过肾脏排泄之前，被血浆α淀粉酶降解为小分子。本品在输入体内后，血浆中羟乙基淀粉的平均分子量为70，000－80，000道尔顿，在治疗期间保持在肾阈值之上。本品分布容积约为升，输注本品30分钟后，血药浓度为最大血液浓度的75%，6小时后降至14%。单次给予羟乙基淀粉500ml，血药浓度在24小时后几乎回到基线水平。单次给予本品500ml后，药物的血浆清除率为为×h,t1/2α为小时，t1/2β为小时，药物的体内药代动力学显示非线性特征。对轻度至重度肾功能不全者进行本品的药代动力学研究，受试者单次给予本品500ml，结果显示，药物的AUC有中等程度的增加，药物在肌肝清除率ClCr<50ml/min的受试者体内AUC为ClCr≥50ml/min受试者体内的倍（95%可信限为－）。肾功能不全不影响药物的消除半衰期和Cmax。当ClCr≥30ml/min时，59%的药物经尿排泄；当ClCr<30ml/min时，51%的药物经尿排泄。对受试者进行的研究显示，每日给予10%羟乙基淀粉130/溶液500ml，连续给药10天，药物在血浆中没有出现明显的蓄积现象。在大鼠模型试验中，每日给予本品按体重，连续给药18天，在末次给药后第52天对组织的药物含量进行检测，结果显示，仅有给药剂量的在组织中储存。尚没有透析疗法对本品药代动力学影响的研究。羟乙基淀粉：是耶？非耶？作者：李妍 编译 来源：中国医学论坛报 日期：2013-02-21 自上世纪60年代上市以来，羟乙基淀粉（HES）在液体复苏中被广泛使用。然而，关于其疗效和安全性的问题一直存在争议。《英国医学杂志》（BMJ）和《美国医学会杂志》（JAMA）先后发表两篇文章，对发表的羟乙基淀粉相关研究进行系统回顾与荟萃分析。在此，我们对两篇文章及JAMA同期配发的述评进行介绍。HES 不能为脓毒症患者带来益处丹麦和瑞士学者检索循证医学图书馆、MEDLINE等数据库，选取2012年9月前发表的比较HES 130/ 和晶体液或人白蛋白对脓毒症患者液体复苏效果和安全性的随机对照临床试验（RCT），最终纳入9 项研究（涉及3456例患者）进行分析。结果显示，与晶体液或白蛋白相比，使用HES 130/ 对脓毒症患者进行液体复苏增加肾脏替代治疗[相对危险度（RR）为]、急性肾功能衰竭（RR=）和红细胞输注风险（RR=），且出现严重不良事件患者更多（RR=）。论文2月15日发表于《英国医学杂志》（BMJ）。HES增重症患者急性肾衰和死亡风险加拿大学者检索MEDLINE、EMBASE等数据库，选取2012年10月前发表的比较在重症患者中使用HES和其他复苏液（包括晶体液、白蛋白和凝胶进行液体复苏的RCT共38项。结果显示，与使用其他复苏液相比，使用HES并不能降低患者死亡率（RR=）；在排除了博尔特（Boldt）进行的7项研究（存在科学性违规行为）后，HES显著增加患者死亡（RR=）和发生急性肾功能衰竭风险（RR=），并增加肾脏替代治疗的使用（RR=）。论文2月20日发表于《美国医学会杂志》[JAMA 2013，309（7）：678]。同期评述用HES 行液体复苏：弊大于利意大利圣心天主教大学 安东内利（Antonelli）和山德罗尼（Sandroni）本次发表于JAMA的荟萃分析提出了一些值得讨论的问题。⑴ 本结果与2012年发表于《科克伦系统综述数据库》的研究结果并不一致。后者未显示HES引起死亡率增加，且排除或不排除Boldt 的研究对结果无影响。当然，该分析仅比较HES 与晶体液，且仅纳入2项Boldt 的研究（死亡率为零）；而本研究纳入7项Boldt的研究（与上述2项不同），且对照组报告了84例死亡，故会对整体结果产生影响。此外，本研究纳入了3项2012年发表的研究，其中的6S 研究为首个报告使用HES显著增加死亡率的研究，且样本量大。⑵ 人们试图通过降低HES 分子量和羟乙基化程度来减少其肾毒性，然而，与林格乳酸盐相比，仍更易造成肾小管损伤。本研究的亚组分析亦证实了这一点。⑶ 本研究强调了在患者安全性评估中出现科学性违规的严重性。2011年3月，14位医学期刊主编发表联合声明，公布了Boldt事件及德国莱茵兰法尔茨国家医学协会（LAK-RLP）对Boldt 医生进行的临床试验的伦理审查结果。其中，80项研究被认为不符合伦理标准或存在科学违规行为。本研究验证了HES的肾毒性，且为首个证明用HES进行急性液体复苏增加死亡率的荟萃分析。 但因比较的液体种类繁多，未能就胶体与晶体液间长期存在的争议提供直接证据。未来须行优质RCT来评估HES 的安全性和有效性。欧美学界曝羟乙基淀粉致肾损伤羟乙基淀粉是一种50多年来广泛用于重症科、麻醉科的临床常用药，被指证“致肾功能损害”。全球顶级3大临床医学期刊(JAMA美国医学会杂志，BMJ英国医学杂志，NEJM新英格兰医学杂志)纷纷发表对其不利的临床研究结果。此事的源头是羟乙基淀粉的倡导者德国教授岳凯姆-伯特(JoachimBoldt)论文造假。丑闻爆发后，欧洲、美国危重学会相继做出不推荐使用的表态。但是，《每日经济新闻》记者调查发现，羟乙基淀粉在中国依然是畅销药物，且销售额逐年攀升，业内保守估计已经超过15亿元。血液紧缺和市场销售额攀升，让国内不少企业积极进行羟乙基淀粉产品的开发和市场开拓，其中包括大输液巨头科伦药业和华润双鹤。对于产品副作用，科伦药业对《每日经济新闻》记者表示，将密切关注临床研究结果，截至记者发稿，华润双鹤方面尚未给予回复。倡导者论文造假引发欧美封杀/日前，国际顶尖医学杂志英国医学杂志BMJ刊登了一篇有关岳凯姆？伯特的文章，标题是《伯特，伟大的造假者》。文章称，岳凯姆？伯特超过90篇羟乙基淀粉临床研究都是闭门造车的产物。羟乙基淀粉是血容量扩容剂，临床上主要用于失血性、创伤性、感染性和中毒性休克等治疗。然而，自上个世纪60年代上市以来，羟乙基淀粉就因其疗效和安全性问题而备受争议。岳凯姆？伯特成为扭转市场的关键性人物。岳凯姆？伯特供职于德国路德维希港大学医学院，是静脉注射药物方面的专家。他在欧洲各大医学杂志上发表了多篇论文论证羟乙基淀粉疗效和安全性，基于他的研究成果，羟乙基淀粉被纳入欧洲不少国家医学指南，成了临床常用药。谎言需要不断累积。2009年，岳 凯 姆？伯 特 一 篇 发 表 在《AnesthesiaandAnalgesia》上的论文因为数据太完美而露出了马脚，不断有读者写信进行质疑，岳凯姆？伯特置之不理的态度使得杂志主编最终对此展开了调查。2010年10月，调查结果让人大吃一惊：此项所谓的临床研究并无伦理委员会同意，甚至连临床试验所需的药品供应商都已经多年未供货。随后的调查则一步步证明了岳凯姆？伯特90多篇论文均为编造的产物。因此，羟乙基淀粉的安全性和有效性被重新考虑。全球顶级的3大临床医学期刊做出了对羟乙基淀粉的不利表态：在有效性方面，羟乙基淀粉不高于同类产品，却会显著增加肾损伤的危险。有效性不高，副作用更多，价格是同类产品10倍，性价比低，导致欧洲和美国危重学会也相继作出了不推荐甚至反对使用的决定。国家食药监总局：目前未关注/据《每日经济新闻》记者了解，在国内，羟乙基淀粉是重症科、麻醉科等科室的常用药物。“欧洲是羟乙基淀粉的发源地，之前使用很多，但是丑闻爆发后用得很少，而美国一直就使用得很少。”中华医学会重症学会的有关人士对《每日经济新闻》记者表示，重症学会不少人对此已经达成共识：临床上谨慎使用，少用。然而，让上述人士担忧的是，很多中国的医生，包括麻醉、外科医生，还不知道羟乙基淀粉的不良作用以及最新证据。在国内最大的面向医生的专业网站丁香园上，揭露岳凯姆？伯特作假以及欧美各国强烈反对一事，呼吁医生们谨慎使用的帖子在麻醉科版面发布后，引起诸多争论，有医生表示“应将此药直接扔进垃圾桶。”也有许多麻醉科医生表示困惑，称此药是常用药，在临床麻醉第一天就接受诸多优点的灌输，还有医生称前几天还受到培训称此药多么好。昨日，记者以麻醉师的身份向国家食药监总局进行咨询，其表示，他们并没有对此药进行关注。记者试图以普通民众的身份了解羟乙基淀粉不良反应信息时，被相关监管部门告知，不良反应信息的内容只是作为对药品进行评价的参考，不对公众开放。不过，国家食药监总局的官方网站显示，2005年的药品不良反应信息通报里，当时的国家药监局就曾发过关于羟乙基淀粉40、20氯化钠注射液对肾功能损害的通报，1988年至2005年3月，国家药品不良反应监测中心病例报告数据库中，有关“706代血浆”、羟乙基淀粉40氯化钠、羟乙基淀粉20氯化钠注射液的病例报告共84例，其中肾功能衰竭1例。当时的国家药监局结论称，建议羟乙基淀粉40、20氯化钠注射液可导致肾损伤，医务人员应严格掌握适应症，避免长期大量、大剂量使用。业内：产品入华或涉嫌商业贿赂/中华医学会重症学会的人士表示，丑闻爆发并未对我国销售造成很大的影响。据了解，2004年，羟乙基淀粉的销售就达到4亿元人民币，现在最保守估计也有15亿元。《每日经济新闻》记者查询发现，在2004年费森尤斯卡比国际临床输血替代学术进展论坛上，岳凯姆？伯特作为专家现身，阐述贺斯 (羟乙基淀粉)的好处。贺斯是费森尤斯卡比公司生产的羟乙基淀粉的商品名，这家公司是目前国内和国际上代血浆市场中份额最大的公司。业内人士表示，国际上不推荐使用，国内却反而用得多，商业贿赂可能起到了作用。一篇网帖的发贴人自称深圳市某医院麻醉科医生，指出该科室一位任职7年的副主任收受高额回扣敛财，涉及金额数千万元。在其所列的收受贿赂的名单中，费森尤斯卡比赫然在列。此事经媒体曝光后，涉事医院很快展开了调查，深圳市纪委也在此前收到举报信，正准备进行调查，并称其违规的事情属实，不过具体金额仍待求证。对于是否进行告知问题，贿赂是否属实的问题，费森尤斯卡比公司未予回应。科伦药业：将密切追踪临床反应在血液及其制品日益紧缺的情况下，国内还有不少厂商对羟乙基淀粉存在浓厚的兴趣，其中包括国内输液巨头华润双鹤和科伦药业。在华润双鹤2009年半年报中，羟乙基淀粉(盈源)被列为重点产品。联讯证券在发表的研报中称，羟乙基淀粉也被列为华润双鹤非基础性输液的重点品种。研报透露，2011年，治疗性输液占公司大输液收入的比例为20%，销量从2010年2500万瓶迅速增长至2011年5200万瓶，同比增长105%。科伦药业对羟乙基淀粉也投入了非常大的精力，且销售额已经相当靠前。在2012年的年报中，科伦药业称其另一产品——羟乙基淀粉乳酸钠林格注射液产业化，已获得发改委通用名化学药发展立项专项。对于是否知道此产品存在副作用，以及是否对产品进行过相关的临床试验，验证其安全性和有效性，截至记者发稿，华润双鹤未给予回复。而科伦药业给《每日经济新闻》记者回复显示，对于岳凯姆？伯特造假和国外学术界对于羟乙基淀粉的反对态度，科伦药业知道得一清二楚。此外，科伦药业还承认羟乙基淀粉在国外的研究中确实出现很多问题，特别是针对肾功能损伤这一副作用。对此，公司将密切追踪该药品的临床反应。不过，科伦药业认为国外权威杂志及危重学会的论断矫枉过正，此产品也未被勒令召回。同时，解放军总医院重症医学教授林洪远也对国外结论提出了质疑。 国内瑞金医院认为此产品还有一定的优势，且国内不少临床医生仍支持配伍使用，所以对产品仍持积极态度。羟乙基淀粉在急救中的临床应用山东省平度市人民医院急诊科、山东省平度市人民医院骨科共同发表论文，旨在探讨羟乙基淀粉130/氯化钠注射液复苏方法对早期失血性休克的临床疗效。研究指出，采用羟乙基淀粉130/氯化钠注射液复苏方法治疗早期失血性休克可增加有效循环血量，改善组织器官灌注，降低病死率。该文章发表在2012年第35卷第24期《中国医师进修杂志》上。 将52例早期失血性休克患者按随机数字表法分为复方氯化钠注射液组(对照组)和羟乙基淀粉130/氯化钠注射液组(治疗组)，每组26例，观察比较两组患者治疗效果，治疗前和治疗后60 min的平均动脉压、呼吸频率和心率以及血钠、血氯和凝血酶原时间。结果显示，治疗组和对照组治愈率分别为(22/26)和(10/26)，病死率分别为(4/26)和(16/26)，两组比较差异均有统计学意义(P<)。治疗组治疗后60 min平均动脉压、心率和呼吸频率均较对照组明显改善[(±)mmHg(1mmHg =)比(±)mmHg、(±)次/min比(±)次/min、(±)次/min比(±)次/min，)。
伴随着社会的发展，人们的食物变得多种多样，功能饮料也顺势而生。但是却有报道说，一名男青年因为每天喝四罐饮料导致了心力衰竭，这是因为每500毫升的功能饮料中，就含有160毫克的牛磺酸和咖啡因，长期大量的摄入这两种药物，是会引发高血压和一切心血管疾病的！
致病的因素是因为他每天喝的饮料其中含有了大量的咖啡因，让血压升高导致了心律失常，所以才会心力衰竭。
中国药理学报英文版《中华临床医学杂志》英文版、《免疫学杂志》、《遗传学和分子生物学医学期刊》、《实验医学杂志》、《美国医学杂志》、 《加拿大医疗协会学报》、给你一个网址，基础医学与生物医学工程栏目里的都是发英文文章的杂志。 如果需要英文医学论文润色.可以看这个网址 医学编辑是美国人,可以提供地道的英文医学论文润色修改服务.
呵呵，问题很差，都没说是什么方向的文章？怎么给您说有哪些？这多了先说文章是什么文章吧
《武汉大学学报》（医学版）是医学核心期刊，如果想发，可以帮你问一下
建议去网上搜搜相关杂志，一定有的。就输medical magazine,或者health magazine
新英格兰医学杂志是电子版的杂志，可以通过网上的数据库看到，国内图书馆的电子资源里面应该可以看，个人的话用pubmed可以搜索到新英格兰医学杂志上的文章。
在文献党下载器资源库可以查询并下载《新英格兰医学》文献
1、在文献党下载器资源库双击“NEJM（新英格兰医学期刊）”名称即可进入该数据库：
（注：首先需要在文献党下载器首页（）下载客户端，登录客户端进入资源库）
例如这篇2022年的文献，点击PDF下载全文：
下载完成：
最新影响因子大预测：CA神刊或突破400分虽然影响因子在生物医学领域不算很高，但是这个杂志却有着很高的国际声誉，影响力巨大。 PNAS也是广受中国学者关注的期刊，2020年中国学者发文占比大约为 %（968/6619 ）仅次于美国，但和美国的 %仍然有较大差异
人食五谷杂粮，总会有生病的时候，这时医学就显得尤为重要。下面是我带来的关于医学方面的英语 文章 ，欢迎阅读!
关于医学方面的英语文章
Joseph Heller’s Catch-22 is one of the most acclaimed novels of the twentieth century. It is a black comedy about life in the military during World War II. It features bombardier John Yossarian, who is trying to survive the military’s inexhaustible supply of bureaucracy and who is frantically trying to do anything to avoid killing and being killed. Heller was able to use his own experiences in the Air Force during World War II to create this character and the novel.
Even though Catch-22 eventually became known as a great novel, it was not originally considered one. When it was first published in 1961, the reviews were tepid and the sales were lackluster. It was not well received at this point at least in part because it presented such a cowardly protagonist at a time when World War II veterans were being lauded for their selfless courage.
Within a few years of the release of the book, as an unpopular war in Southeast Asia was heating up, Heller’s Catch-22 found a new audience eager to enjoy the exploits of Heller’s war-averse protagonist. It was within the framework of this era that Catch-22 was newly discovered, newly examined, and newly credited as one of the century’s best novels.
Let me talk a bit about the expression catch-22. Do you understand what a catch-22 is? This expression is so well known now that it has entered the American lexicon: well, a catch-22 is a situation that is unresolvable, one where there is no good choice, not best path to take.
In Heller’s novel, the catch-22 is a very specific catch in a very specific situation. The situation in which the protagonist found himself was that he wanted to get out of combat by declaring himself insane. So you see that in this situation, there was a very specific catch. In American culture now, though, this expression is used more generally. It refers to any situation where there’s a catch, where there’s no solution, where there’s no way out.
One more bit of information about the expression catch-22, about the number 22 in the expression. This number doesn’t have any real meaning; it just signifies one in a long line of catches. Heller really could have used any number; it didn’t have to be 22. When Heller was first writing the book, he used the number 14; the book was originally titled Catch-14. Then, in the production process, the number was changed to 18, so the title was Catch-18. But then there was a problem with the number 18 because there was another book with 18 in the title, so Heller’s title became Catch-22.
Hemophilia is a condition in which the blood either clots slowly or fails to clot at all. Most people who get a little cut on a finger can put a bandage on the cut, and the cut on the finger will heal because the blood will clot. A blood clot forms from the polymerization of protein fibers that circulate in the blood. A number of protein factors take part in the process, and it is necessary for all of the protein factors to function correctly for blood to clot. Hemophilia exists when any of the factors is either missing or not functioning.
The most common kinds of hemophilia are hemophilia A (or classic hemophilia) and hemophilia B (or Christmas hemophilia), which was named after the first person known to have contracted it. Hemophilia A occurs when clotting factor 8 is not functioning properly; 85% of those who suffer from hemophilia have hemophilia type A. Hemophilia B occurs when factor 9 is not functioning properly; almost all of the rest of those who suffer from hemophilia have hemophilia B.
Hemophilia is generally passed from mother to son, though sometimes it seems to develop spontaneously in some women. Women carry recessive gene but do not generally develop the disease. A mother who carries the defective gene may or may not pass it on to her children. If a mother passes the defective gene to a daughter, the daughter will carry the gene but will most likely not develop the disease. If a mother passes the defective gene to a son, then the son will most likely develop the disease.
Probably the most famous case of hemophilia is often called Royal hemophilia. In this case, Queen Victoria of England, who lived from 1819-1901, was a carrier of the mutating factor 8 that leads to hemophilia type A. Queen Victoria may have inherited the mutated gene from one of her parents, though there is no sign of the mutated gene in the families of Victoria’s parents up to that time that she was born. The mutated factor 8 may also have mutated spontaneously in Victoria, as seems to happen sometimes.
However Victoria came to be a carrier of the gene with the mutated factor, she unfortunately passed it on to some of her children. She had nine children, and three of them, her daughters Alice and Beatrice and her son Leopold, received the mutated gene from their mother. Victoria’s daughters then intermarried with other royal houses of Europe and carried the disease with them. Through Queen Victoria’s daughter Beatrice, the disease was carried into the royal family of Spain. Through Queen Victoria’s daughter Alice, the disease was introduced into the royal families of Austria and Russia, though the disease no longer exists in the Russian family because Victoria’s granddaughter Alexandra and her children were all killed during the Russian revolution.
当今,由于人类社会的发展,生活节奏的加快,对于中年人群体老年疾病提前到来。中年人由于疾病的缠身,生活质量的下降等原因,给家庭和社会带来了很大的负面影响。下面是我带来的医学类英语 文章 ，欢迎阅读!
医学类英语文章1
指甲油、发胶或增加糖尿病风险
Chemicals commonly found in beauty products such as nail polishes, hair sprays andperfumesmay increase risk of diabetes for some women, new research suggests.
Chemicals commonly found in beauty products such as nail polishes, hair sprays andperfumesmay increase risk of diabetes for some women, new research suggests.
Researchers analyzed urine samples from 2,350 women who participated in the long-runningNational Health and Nutrition Examination Survey, a nationally representative sampleof Americanwomen. They were looking for concentrations of chemicals known as phthalates,which are oftenfound in personal care products and in adhesives, electronics, products used tomanufacture cars, toys, packaging and even some coatings for medications.
Phthalates are considered "endocrine-disrupting" because they can alter normal regulationofcertain mechanisms in the body, including hormone regulation, and have been tied inpreviousresearch to diabetes and obesity risk, Dr. Kenneth Spaeth, director of theOccupational andEnvironmental Medicine Center's department of population health at NorthShore UniversityHospital in Manhasset, ., told HealthPop. He was not involved in the study.
The researchers found that women with the highest concentrations of two types of phthalates -mono-benzyl phthalate and mono-isobutyl phthalate - were nearly two times more likely tohavediabetes compared to women with the least amounts of these chemicals. Women withmoderatelyhigh levels of the phthalates mono-n-butyl phthalate and di-2-ethylhexyl phthalatewere 70 percent more likely to have diabetes compared to their counterparts.
The findings were published in Environmental Health Perspectives, a journal published bythegovernment's National Institute of Environmental Health Sciences.
"This is an important first step in exploring the connection between phthalates and diabetes,"saidDr. Tamara James-Todd, a researcher in women's health at Brigham and Women's HospitalinBoston, said in a press release. The researchers could not prove that phthalates causeddiabetes orhaving diabetes increased concentrations of the chemicals in a person's body.
"We know that in addition to being present in personal care products, phthalates also existincertain types of medical devices and medication that is used to treat diabetes and this couldalsoexplain the higher level of phthalates in diabetic women," she added. "So overall, moreresearch isneeded."
One of the problems is that chemicals like phthalates are practically unavoidable, accordingtoSpaeth.
"These chemicals are unfortunately ubiquitous," Spaeth explained. "It's pretty clear fromstudiesthat we're exposed all day long to these various household or personal care products."
Spaeth says it's a real challenge to reduce phthalate exposure because sometimes thechemical is ametabolic byproduct of another ingredient or a product label may not say itcontains phthalatesonly for phthalates to be found in the packaging the product came in, whichdoes not need to bementioned on a product label.
"It's really hard to make informed decisions about these kinds of things," he said. "Maybe we'llgetto a point when the health effects are more widely recognized, that there will be incentivetochange how products are made and packaged."
However Spaeth did say research has shown phthalates can find their way into householddustand people sometimes ingest them that way, so simple steps like frequent vaccuming anddusting, or washing your hands regularly before eating may decrease risk.
医学类英语文章2
西方快餐与亚洲人患心脏病风险存在联系
Even relatively clean-living Singaporeans who regularly eat burgers, fries and other staplesof fast food are at a raised risk of diabetes and more likely than their peers to die ofheart disease, according to an international study.
at a raised risk of diabetes：提高患糖尿病的风险
But Asian fast foods, such as noodles or dumplings, did not bear the same risk, the studypublished in the journal Circulation said.
bear the same risk：承受同样的风险
the journal Circulation：《循环》杂志
With globalization, fast food has become commonplacein East and SoutheastAsia. The study looked at more than 60,000 Singaporeans of Chinese descent.
"Many cultures welcome (Western fast food) because it's a sign they're developing theireconomics," said Andrew Odegaard, from the University of Minnesota School of Public Health,who led the study.
the University of Minnesota School of Public Health：明尼苏达大学的公共卫生学院
"But while it may be desirable from a cultural standpoint, from a health perspective theremay be a cost," he told Reuters Health.
a cultural standpoint： 文化 角度
The study participants were interviewed in the 1990s, then followed for about a decade.
Participants were between 45 and 74 years old at the outset. During the study period, 1,397 died of cardiac causes and 2,252 developed type 2 diabetes.
died of cardiaccauses：死于心脏病
Those who ate fast food two or more times a week had 27 percent greater odds ofdiabetes and 56 percent higher risk of cardiac death than those who ate little or no fast food,the researchers found.
greater odds of：更大的几率
Among 811 subjects who ate Western-style fast food four or more times a week, the riskof cardiac death rose by 80 percent.
Western-style fast food：西式快餐
The findings held even after the researchers adjusted for other factors that could influencehealth, including age, sex, weight, smoking status and education level.
In fact, the Singaporeans who ate Western fast food often were more likely to be younger,educated and physically active, and were less likely to smoke, than those who stuck to a moretraditional diet.
physically active：体力活动
Odegaard's team found that Eastern fast foods, such as dim sum, noodles and dumplings,were not associated with more cases of type 2 diabetes and cardiac deaths.
dim sum：中式点心
be not associated with:与……无关
"It wasn't their own snacks that was putting them at increased risk, but American-style fastfood," he said.
The profile of the fast food eaters differs markedly from that of the average fast foodconsumer in the United States, he added, with eating fast food in countries like Singapore astatus symbol and a way of "participating in American culture".
a status symbol：身份象征
The findings hold serious implications for recently developed and emerging countries, saidSara Bleich, an assistant professor of health policy at Johns Hopkins Bloomberg School of PublicHealth in Baltimore.
hold serious implications for：对……有严重影响
Johns Hopkins Bloomberg School of Public Health：约翰霍普金斯大学彭博公共卫生学院
"The big multinational fast food companies are increasingly looking to maximize profitoutside the United States, and they're looking to emerging economies like Singapore to dothat," she said. "So at the global level, the health implications are very strong."
maximize profit：追求利润最大化
emerging economies：新兴市场国家
医学类英语文章3
胖子的 记忆力 思考力下降快
Fatter people are more likely to lose their memories and brain power quicker than thosewho are thinner, according to British research.
据英国某一研究，相比瘦子，胖子的记忆力和脑力下降得更快。
Those who are obese, and have other health problems such as high blood pressure andhigh cholesterol, lose their memory and thinking skills almost a quarter faster, foundresearchers at University College London.
英国伦敦大学学院的一份研究表明，那些患有如高血压高胆固醇等健康问题的胖子和那些一般的胖子，比起瘦子来说，他们的记忆力和脑力下降速度要快四分之一。
Their study was based on almost 6,500 Whitehall civil servants, whose health wasmonitored between the ages of 50 and 60.
这份研究以将近6,500名年龄在50岁到60岁之间的白厅(英国)公务员的健康状况为研究对象。
They were weighed and measured, their blood pressure and cholesterol levels were taken,and they were also asked what medication they were taking.
研究人员对他们称了体重，做了测量，记录了他们的血压和胆固醇含量，同时还了解了他们目前在做哪些药物治疗。
In addition, they were asked to perform mental tests three times during the decade,which were used to assess memory and other cognitiveskills.
此外，研究对象在这十年时间里还要参加三次智力测验，这些测验结果将作为评估记忆和 其它 认知技能的依据。
Of the 6,401 civil servants in the study, nine per cent (582) were obese. Of those, 350 werealso classed as “metabolicallyabnormal”- meaning they had two additional risk factors such ashigh blood pressure, high cholesterol, were taking medication for either condition, or werediabetic.
在参与这项研究的6,401名国家公务员中，9%(即582人)是胖子。有350人的新陈代谢存在异常现象，这也意味着他们将面临双重危险，高血压和高胆固醇。他们需要服用治疗高血压和高胆固醇的药物。除此以外还有糖尿病患者。
The researchers found the obese tended to lose their mental powers faster than theirthinner colleagues, while those who also had additional conditions lost their memory andthinking skills fastest of all.
研究人员发现胖子比起他们的瘦子同事更容易失去大脑思考能力，而这个人群中最容易失忆和失去思考能力的是这些还有其它健康问题的胖子。
The latter group experienced a percent faster decline on their cognitive test scoresover the decade than those who were healthy.
比起健康的胖子，后一组研究对象(指还有其它健康问题的胖子)在过去的十年时间里在认知测试中得分下降高达。
Archana Singh-Manoux, of the Paris research institute Inserm, who contributed to thestudy, said their results indicated the idea that people could be obese but still healthy wasflawed.
巴黎研究机构Inserm的辛格-曼诺(Archana Singh-Manoux)负责这项研究。他说，他们的研究结果表明胖子是健康的这一看法是站不脚的。
Shirley Cramer, chief executive of Alzheimer’s Research UK, said: “We do not yet know whyobesity and metabolic abnormality are linked to poorer brain performance, but with obesitylevels on the rise, it will be important to delvea little deeper into this association.
英国老年痴呆症研究所的主管雪莉·克莱默(Shirley Cramer)说：“目前我们还不知道为什么肥胖与新陈代谢异常这两方面会和脑力衰弱有联系。但是随着肥胖程度的增加，进一步深入探究它们之间的关联将变得很重要。”
“While the study itself focuses on cognitive decline, previous research suggests that ahealthy diet, regular exercise, not smoking and controlling blood pressure and cholesterol inmidlife can also help stave off dementia."
“虽然这项研究本身关注的是认知能力的减弱，但先前的研究表明在中年时期，健康的饮食、定期锻炼、不吸烟、控制血压和胆固醇等有助于减缓痴呆症的产生。”
专门的循证医学期刊里SCI的很少，据我所知只有心理学和替代医学有。如果不强求SCI，有三本刊可以投：Evidence-basedMedicine,Evidence-basedNursing和Evidence-basedMentalHealth。其实循证医学可以投的SCI期刊很多，尤其是综合期刊，比如BMJOpen就欢迎循证医学文章。
比较好SCI呼吸学期刊有Thorax，影响因子，全球第四。它的线上版期刊叫BMJ Open Respiratory Research，临床基础研究都收，新刊，已经进了PubMed，进SCI指日可待，说不定现在投了，接收时就是SCI了。或者投之后一两年进了SCI，你的文章仍然可以在SCI数据库检索到