Fuels operated in filling stations having flammable and explosive properties often cause fire and explosion incidents. This paper described a safety assessment on major risk sources, dangerous factors, storage and operational conditions of petroleum products in Lingshan Luwuzengli filling station mainly using Safety Checklists (SCL), Fault Tree Analysis (FTA), and Dow's Index of Fire Explosion (DOW), etc. The author understood the causes for incidents in filling stations through the above-mentioned assessment methods and summarized and analyzed problems presented in current filling stations (重复语句,免译) in details, and put forward specific safety management measures for reduction of incidents and professional harms for Luwuzengli filling station, concerning about the developmental status and trends, as well as the requirement of of the whole fuel-filling industry.