Abstract: March 2008 to May of a pet hospital in Hefei Jiezhenbingquan, three cases of the clinical symptoms observed, rapid detection test carton diagnosis, diagnosed as dogs and canine distemper virus of canine parvovirus infection. Canine distemper virus and canine parvovirus infection of the main high fever, cough, a shame that, conjunctivitis, vomiting, diarrhea, bloody row, the decline in the total number of leukocytes, lymphocytes percentage increase for the features. The difficulties of treatment, early diagnosis, effective treatment reasonable to antibacterial anti-inflammatory, secondary infection control, energy regulation body fluids added acid-base balance, monoclonal antibodies and in the virus, enhance immunity and symptomatic treatment principle, can improve governance The more rates. After treatment and prevention of the disease to livestock owners the corresponding guidance and recommendations to effectively improve the animal epidemic prevention main awareness of this parvovirus (Canine Parvovirus virus)Canine distemper virus (Canine distemper virus)