Mu Xiang Shun Qi Wan Medicine ResearchesIn vitro anti-Helicobacter pylori action of 30 Chinese herbal medicines used to treat ulcer Li Y, Xu C, Zhang Q, Liu JY, Tan RXInstitute of Functional Biomolecules, State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR CInfection by Helicobacter pylori has been ascertained to be an important etiologic impetus leading usually to chronic active gastritis and gastric ulcer with growing incidences Utilizing as the test pathogen a standard and five clinic strains of Helicobacter pylori, the antibacterial action was assessed in vitro with ethanol extracts of 30 Chinese herbal medicines which have been frequently prescribed since ancient times for treating gastritis-like Among the 30 tested materials, the ethanol extracts of Abrus cantoniensis (Fabaceae), Saussurea lappa (Asteraceae) and Eugenia caryophyllata (Myrtaceae) were strongly inhibitory to all test strains (MICs: approximately 40 microg/ml), and Hippophae rhamnoides (Elaeagnaceae), Fritillaria thunbergii (Liliaceae), Magnolia officinalis and Schisandra chinensis (Magnoliaceae), Corydalis yanhusuo (Papaveraceae), Citrus reticulata (Rutaceae), Bupleurum chinense and Ligusticum chuanxiong (Apiaceae) substantially active with MICs close to 0 microg/ As to antibacterial actions of the aqueous extracts of the same drugs, those derived from Cassia obtusifolia (Fabaceae), Fritillaria thunbergii and Eugenia caryophyllata were remarkably inhibitory against all the six Helicobacter pylori strains (MICs: approximately 60 microg/ml) The work compared almost quantitatively the magnitude of the anti-Helicobacter pylori actions of the 30 most prescribed gastritis-treating Chinese herbal drugs, and located as well some source plants where potent anti-Helicobacter pylori phytochemicals could be Pharmacokinetic and pharmacological interactions between ticlopidine hydrochloride and Kangen-Karyu - Chinese traditional herbal Makino T, Wakushima H, Okamoto T, Okukubo Y, Deguchi Y, Kano YDepartment of Kampo Medicinal Science, Hokkaido College of Pharmacy, 7-1 Katsuraoka, Otaru 047-0264, JapanKangen-Karyu (KGK), containing peony root, cnidium rhizome, saf flower, cyperus rhizome, saussurea root and Salvia miltiorrhiza root, is a Chinese traditional medicine formula to invigorate the 'blood' and dispel 'blood stasis', arising from poor blood The present study evaluated the pharmacokinetic and pharmacological interactions between KGK and ticlopidine Ticlopidine was administered orally or intravenously to KGK-treated rats, and its plasma concentrations were KGK did not significantly affect the pharmacokinetic parameters of ticlopidine in rats treated with both oral and intravenous Ticlopidine alone significantly prolonged the mouse tail-bleeding time and adenosine 5'-diphosphate-induced ex vivo platelet aggregation, which was slightly augmented by KGK It is suggested that the combined therapy of ticlopidine and KGK may augment the antithrombotic effects, and that the dosage of ticlopidine should be reduced to prevent thrombotic thrombocytopenic purpura, a severe adverse effect of Bioactive constituents from Chinese natural XV Inhibitory effect on aldose reductase and structures of Saussureosides A and B from Saussurea Xie H, Wang T, Matsuda H, Morikawa T, Yoshikawa M, Tani TKyoto Pharmaceutical University, JThe 80% aqueous acetone extract from the whole plant of Saussurea medusa MAXIM was found to inhibit rat lens aldose reductase (IC50=4 microg/ml) From this extract, flavonoids, lignans, and quinic acid derivatives were isolated together with two new ionone glycosides, saussureosides A and B Their absolute stereostructures were elucidated on the basis of chemical and physicochemical evidence including the application of modified Mosher's In addition, some isolates were found to show an inhibitory effect on aldose This is the page of Chinese medicine for stomach problems, you can buy Mu Xiang Shun Qi Wan online